{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-30",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "effective_time": "20191003",
      "inactive_ingredient": [
        "Aloe Barbadensis Leaf Juice, Nerium Oleander Leaf Extract (NAE8®), Water (Aqua), Propanediol, Hydrolyzed Egg Shell Membrane (Peptide Matrix – Collagen & Elastin), Cetyl Alcohol, Glycerin, Glyceryl Stearate, Potassium Cetyl Phosphate, Cetearyl Olivate, Caprylic/Capric Triglyceride, Dimethicone, Ricinus Communis (Castor) Seed Oil, Glyceryl Caprylate, Sorbitan Olivate, Lysolecithin, Sclerotium Gum, Xanthan Gum, Allantoin, Arginine, Avena Sativa Kernel Flour (Colloidal Oatmeal), Butyrospermum Parkii (Shea) Butter, Olea Europaea (Olive) Fruit Oil, Pelargonium Graveolens (Geranium) Flower Oil, Tocopherol, Fragrance, Leuconostoc/Radish Root Ferment Filtrate, Pullulan, Ocimum Basilicum (Basil) Extract, Linum Usitatissimum (Linseed) Seed Oil, Carum Petroselinum (Parsley) Extract, Benzyl Alcohol, Potassium Sorbate, Dipotassium Glycyrrhizate, Glyceryl Undecylenate, Sea Salt, Mahonia Aquifolium (Oregon Grape) Root Extract, Sodium Benzoate, Muriella Aurantiaca/Ruttnera Lamellosa Oil (Plankton Extract), Citric Acid, Lecithin"
      ],
      "instructions_for_use": [
        "• Clean the skin thoroughly before applying this product. • Cover the entire affected area with a thin layer one to three times daily. • Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two to three times daily if needed or as directed by a doctor. • If bothersome dryness or peeling occurs, reduce application to once a day or every other day. • Sensitivity Test for a New User . Apply product sparingly to one or two small affected ares during the first 3 days. If no discomfort occurs, follow the directions stated above."
      ],
      "purpose": [
        "Acne Treatment Cream"
      ],
      "keep_out_of_reach_of_children": [
        "If swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "warnings": [
        "For external use only.​ When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. If swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "when_using": [
        "When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time."
      ],
      "questions": [
        "1-(844)-599-7787 M-F (9 am to 5 pm CST)"
      ],
      "spl_product_data_elements": [
        "PURE NERIUM ACNE THERAPY Salicylic Acid 2.0% MEDIUM-CHAIN TRIGLYCERIDES GLYCERYL 1-UNDECYLENATE PULLULAN GLYCYRRHIZINATE DIPOTASSIUM LEUCONOSTOC/RADISH ROOT FERMENT FILTRATE NERIUM OLEANDER LEAF WATER BETASIZOFIRAN XANTHAN GUM OATMEAL SHEA BUTTER TOCOPHEROL SALICYLIC ACID SALICYLIC ACID EGG SHELL MEMBRANE GLYCERYL STEARATE SE PELARGONIUM GRAVEOLENS FLOWER OIL CETYL ALCOHOL GLYCERIN POTASSIUM CETYL PHOSPHATE CETEARYL OLIVATE RICINUS COMMUNIS SEED GLYCERYL CAPRYLATE ANHYDROUS CITRIC ACID SODIUM BENZOATE MAHONIA AQUIFOLIUM ROOT LECITHIN, SOYBEAN OCIMUM BASILICUM WHOLE PROPANEDIOL LINSEED OIL PARSLEY BENZYL ALCOHOL POTASSIUM SORBATE SEA SALT DIMETHICONE SORBITAN OLIVATE LYSOPHOSPHATIDYLCHOLINE, SOYBEAN ALLANTOIN ARGININE OLIVE OIL ALOE VERA LEAF"
      ],
      "other_safety_information": [
        "Not recommended for use by pregnant or nursing women."
      ],
      "openfda": {},
      "version": "1",
      "dosage_and_administration": [
        "2% Topical Cream"
      ],
      "storage_and_handling": [
        "Transport and store in a cool dry place and keep away from direct sunlight."
      ],
      "package_label_principal_display_panel": [
        "Principal Display Panel PURE NERIUM® ACNE THERAPY CREAM WITH SALICYLIC ACID PATENTED NERIUM ALOE EXTRACT NAE-8®",
        "PURE NERIUM® -ACNE THERAPY CREAM, 30.3g/1.07 FL.OZ. 30.3g/1.07FL.OZ."
      ],
      "indications_and_usage": [
        "• For the treatment of acne. • Dries and clears acne blemishes, acne pimples, blackheads, whiteheads and allows skin to heal. • Penetrates pores to control acne blemishes, acne pimples, blackheads, whiteheads. • Helps keep skin clear of new acne blemishes, acne pimples, blackheads, whiteheads."
      ],
      "set_id": "940a2e5d-f348-5398-e053-2995a90acc08",
      "id": "940a2edc-ab2e-fb8a-e053-2a95a90a89b4",
      "active_ingredient": [
        "Salicylic acid 2.0%."
      ]
    }
  ]
}