{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-28",
    "results": {
      "skip": 0,
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  "results": [
    {
      "spl_product_data_elements": [
        "Itch Relief Diphenhydramine HCl and Zinc Acetate DIPHENHYDRAMINE HYDROCHLORIDE DIPHENHYDRAMINE ZINC ACETATE ZINC CATION GLYCERIN ALCOHOL TROMETHAMINE ALOE BARBADENSIS LEAF WATER"
      ],
      "active_ingredient": [
        "Active ingredients Diphenhydramine HCl 2.0%, Zinc Acetate 0.1%"
      ],
      "purpose": [
        "Purpose External analgesic Skin protectant"
      ],
      "indications_and_usage": [
        "Uses for the temporary relief of pain and itching associated with: minor burns sunburn minor cuts scrapes insect bites minor skin irritations rashes due to poison ivy, poison oak and poison sumac dries the oozing and weeping of poison ivy, poison oak and poison sumac"
      ],
      "warnings": [
        "Warnings For external use only. Flammable: Keep away from fire or flame. Do not puncture or incinerate. Contents under pressure. Do not store at temperatures above 120°F. Intentional misuse by delibrately concenrating and inhaling contents can be harmful or fatal. ​Do not use on large areas of the body with any other product containing diphenhydramine, even one taken by mouth Ask a doctor before use on chicken pox on measles When using this product avoid contact with eyes ​Stop use and ask doctor if conditions worsens symptoms last more than 7 days or clear up and occur again within a few days ​Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.",
        "Ask a doctor before use on chicken pox on measles"
      ],
      "safe_handling_warning": [
        "Flammable: Keep away from fire or flame. Do not puncture or incinerate. Contents under pressure. Do not store at temperatures above 120°F. Intentional misuse by delibrately concenrating and inhaling contents can be harmful or fatal."
      ],
      "do_not_use": [
        "​Do not use on large areas of the body with any other product containing diphenhydramine, even one taken by mouth"
      ],
      "when_using": [
        "When using this product avoid contact with eyes"
      ],
      "stop_use": [
        "​Stop use and ask doctor if conditions worsens symptoms last more than 7 days or clear up and occur again within a few days"
      ],
      "keep_out_of_reach_of_children": [
        "​Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions do not use more often than directed adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily children under 2 years of age: ask a doctor"
      ],
      "other_safety_information": [
        "Other information store between 20° to 25°C (68° to 77°F)"
      ],
      "inactive_ingredient": [
        "Inactive ingredients aloe barbadensis leaf juice, glycerin, purified water, SD alcohol 40-B, tromethamine"
      ],
      "questions": [
        "Questions? 1-866-964-0939"
      ],
      "recent_major_changes": [
        ""
      ],
      "package_label_principal_display_panel": [
        "Principal Display Panel CVS Extra Strength ITCH RELIEF SPRAY Diphenhydramine HCl 2% Topical Analgesic Zinc Acetate 0.1% Skin Protectant Compare to Benadryl® Extra Strength Itch Cooling Spray active ingredients* Relieves Itching From : Insect bites, Poison ivy, oak & sumac Soothes Sunburn, Minor Burns & Cuts Sprays at Any Angle For Topical Use Only NET WT 2.7 OZ (76g) carton"
      ],
      "set_id": "7e921988-ec66-38dc-e053-2a91aa0a7346",
      "id": "4e68977a-63bb-1af9-e063-6394a90a737e",
      "effective_time": "20260401",
      "version": "8",
      "openfda": {
        "application_number": [
          "M017"
        ],
        "brand_name": [
          "Itch Relief"
        ],
        "generic_name": [
          "DIPHENHYDRAMINE HCL AND ZINC ACETATE"
        ],
        "manufacturer_name": [
          "CVS Pharmacy"
        ],
        "product_ndc": [
          "69842-235"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "TOPICAL"
        ],
        "substance_name": [
          "DIPHENHYDRAMINE HYDROCHLORIDE",
          "ZINC ACETATE"
        ],
        "rxcui": [
          "1053138"
        ],
        "spl_id": [
          "4e68977a-63bb-1af9-e063-6394a90a737e"
        ],
        "spl_set_id": [
          "7e921988-ec66-38dc-e053-2a91aa0a7346"
        ],
        "package_ndc": [
          "69842-235-27"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "TC2D6JAD40",
          "FM5526K07A"
        ]
      }
    }
  ]
}