{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-28",
    "results": {
      "skip": 0,
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  "results": [
    {
      "spl_product_data_elements": [
        "Salicylic Acid Astringent ALCOHOL ALOE BENZOPHENONE DENATONIUM BENZOATE DIMETHICONE GLYCERIN ISOCETETH-20 POLYETHYLENE GLYCOL 1500 SODIUM CITRATE WATER FD&C BLUE NO. 1 SALICYLIC ACID SALICYLIC ACID"
      ],
      "active_ingredient": [
        "Active ingredient Salicylic acid 0.5%"
      ],
      "purpose": [
        "Purpose Acne medication"
      ],
      "indications_and_usage": [
        "Use for the treatment of acne"
      ],
      "warnings": [
        "Warnings For external use only Flammable. Keep away from fire or flame."
      ],
      "when_using": [
        "When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time"
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions clean the skin thoroughly before applying this product cover the entire affected area with a thin layer and rinse thoroughly one to three times daily because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor if bothersome dryness or peeling occurs, reduce daily application to once a day or every other day"
      ],
      "inactive_ingredient": [
        "Inactive ingredients alcohol (24.5%), algae extract, aloe barbadensis leaf extract, benzophenone-4, denatonium benzoate, dimethicone propyl PG-betaine, fragrance, glycerin, isoceteth-20, PEG-32, propylene glycol, sodium citrate, water, blue 1"
      ],
      "questions": [
        "Questions or comments? 1-888-423-0139"
      ],
      "adverse_reactions": [
        "ADVERSE REACTION *This product is not manufactured or distributed by Johnson & Johnson Consumer Products Company, distributor of Clean & Clear ® Sensitive Skin Deep Cleaning Astringent. Visit us here for more information: http://topbrands.com DISTRIBUTED BY TOPCO ASSOCIATES LLC 150 NORTHEST POINT BOULEVARD ELK GROVE VILLAGE, IL 60007 1-888-423-0139 TOPCO VIJA0119 topcare@ topco.com QUALITY GUARANTEED"
      ],
      "package_label_principal_display_panel": [
        "principal display panel TopCare beauty™ DEEP CLEANING ASTRINGENT Salicylic Acid Acne Medication Compare to CLEAN & CLEAR ® * Gentle formula that treats & helps prevent pimples Sensitive Skin 8 FL OZ (237 mL) image description image description"
      ],
      "set_id": "7d15560f-d8d1-4dfe-8eca-b16bb529ad87",
      "id": "4ab9e538-f943-9d4c-e063-6394a90a30ce",
      "effective_time": "20260213",
      "version": "13",
      "openfda": {
        "application_number": [
          "M006"
        ],
        "brand_name": [
          "Salicylic Acid"
        ],
        "generic_name": [
          "ASTRINGENT"
        ],
        "manufacturer_name": [
          "Topco Associates LLC"
        ],
        "product_ndc": [
          "36800-875"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "TOPICAL"
        ],
        "substance_name": [
          "SALICYLIC ACID"
        ],
        "rxcui": [
          "199308"
        ],
        "spl_id": [
          "4ab9e538-f943-9d4c-e063-6394a90a30ce"
        ],
        "spl_set_id": [
          "7d15560f-d8d1-4dfe-8eca-b16bb529ad87"
        ],
        "package_ndc": [
          "36800-875-34"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "O414PZ4LPZ"
        ]
      }
    }
  ]
}