{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-28",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "ZITFREE ACNE TREATMENT BENZOYL PEROXIDE BENZOYL PEROXIDE BENZOYL PEROXIDE CARBOMER HOMOPOLYMER TYPE C (ALLYL PENTAERYTHRITOL CROSSLINKED) EDETATE DISODIUM HYPROMELLOSE, UNSPECIFIED LAURETH-4 METHYLPARABEN WATER SODIUM HYDROXIDE"
      ],
      "spl_unclassified_section": [
        "Drug Facts"
      ],
      "active_ingredient": [
        "Active ingredient Benzoyl peroxide 10%"
      ],
      "purpose": [
        "Purpose Acne treatment"
      ],
      "indications_and_usage": [
        "Uses treats acne dries acne pimples and allows skin to heal helps prevent new acne pimples from forming"
      ],
      "warnings": [
        "Warnings For external use only. Do not use if you have very sensitive skin are sensitive to benzoyl peroxide When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time avoid unnecessary sun exposure and use a sunscreen avoid contact with the eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. Stop use and consult a doctor if irritation becomes severe. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of accidental ingestion, get medical help or contact a Poison Control Center right away: 800-222-1222."
      ],
      "do_not_use": [
        "Do not use if you have very sensitive skin are sensitive to benzoyl peroxide"
      ],
      "when_using": [
        "When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time avoid unnecessary sun exposure and use a sunscreen avoid contact with the eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration."
      ],
      "stop_use": [
        "Stop use and consult a doctor if irritation becomes severe."
      ],
      "pregnancy_or_breast_feeding": [
        "If pregnant or breast-feeding, ask a health professional before use."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children. In case of accidental ingestion, get medical help or contact a Poison Control Center right away: 800-222-1222."
      ],
      "dosage_and_administration": [
        "Directions Sensitivity Test for a New User. Apply product sparingly to one or two small affected areas during the first 3 days. If no discomfort occurs, follow the directions stated below clean the skin thoroughly before applying this product cover the entire affected area with a thin layer up to 3 times daily because excessive drying of the skin may occur, start with 1 application daily, then gradually increase to 2 to 3 times daily if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day if going outside, use sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor."
      ],
      "storage_and_handling": [
        "Other information store at 15 to 30°C (59 to 86°F) Tamper Evident: DO NOT USE IF SEAL ON TUBE IS BROKEN OR MISSING."
      ],
      "inactive_ingredient": [
        "Inactive ingredients carbomer, disodium EDTA, hydroxypropyl methylcellulose, laureth-4, methylparaben, purified water, sodium hydroxide"
      ],
      "questions": [
        "Questions or comments? 866-323-0107 or visit www.natureplex.com"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 28 g Tube Carton NDC 67234-035-01 Natureplex ™ MAXIMUM STRENGTH Zit Free Acne Treatment Cream * Compare to the active ingredient of Clearasil ® Daily Clear ® Vanishing Acne Treatment Cream Oil-Free, Odorless Cream Disappears As It Works NET WT 1 OZ (28g) Principal Display Panel - 28 g Tube Carton"
      ],
      "set_id": "70c2e3fb-e643-467b-80fd-c40e3c3e9513",
      "id": "54742c5c-0537-49fa-bf1f-6152a8cdb0a8",
      "effective_time": "20260129",
      "version": "3",
      "openfda": {
        "application_number": [
          "M006"
        ],
        "brand_name": [
          "ZITFREE ACNE TREATMENT"
        ],
        "generic_name": [
          "BENZOYL PEROXIDE"
        ],
        "manufacturer_name": [
          "Natureplex, LLC"
        ],
        "product_ndc": [
          "67234-035"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "TOPICAL"
        ],
        "substance_name": [
          "BENZOYL PEROXIDE"
        ],
        "spl_id": [
          "54742c5c-0537-49fa-bf1f-6152a8cdb0a8"
        ],
        "spl_set_id": [
          "70c2e3fb-e643-467b-80fd-c40e3c3e9513"
        ],
        "package_ndc": [
          "67234-035-01"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "W9WZN9A0GM"
        ]
      }
    }
  ]
}