{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-29",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest plus Tartar Protection Whitening Sodium Fluoride POLYSORBATE 80 POLOXAMER 407 SUCRALOSE COCAMIDOPROPYL BETAINE DISODIUM PYROPHOSPHATE HYDRATED SILICA WATER SORBITOL SODIUM HYDROXIDE SODIUM LAURYL SULFATE SACCHARIN SODIUM XANTHAN GUM TITANIUM DIOXIDE SODIUM FLUORIDE FLUORIDE ION"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "Dist. by Procter & Gamble, Cincinnati, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243%"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, sodium hydroxide, flavor, xanthan gum, sodium saccharin, poloxamer 407, cocamidopropyl betaine, sucralose, polysorbate 80, titanium dioxide"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "recent_major_changes": [
        ""
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 161 g Tube Carton Crest plus FLOURIDE ANTICAVITY TOOTHPASTE NET WT 5.7 OZ (161 g) TARTA PROTECTION WHITENING HELPS PREVENT TARTAR & WHITENS TEETH COOL MINT PASTE label"
      ],
      "set_id": "560980ea-749f-593d-e063-6394a90a1b9e",
      "id": "560980f2-39de-62f1-e063-6294a90aa419",
      "effective_time": "20260601",
      "version": "1",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest plus Tartar Protection Whitening"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "84126-670"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "891775"
        ],
        "spl_id": [
          "560980f2-39de-62f1-e063-6294a90aa419"
        ],
        "spl_set_id": [
          "560980ea-749f-593d-e063-6394a90a1b9e"
        ],
        "package_ndc": [
          "84126-670-24",
          "84126-670-57",
          "84126-670-82"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}