{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-29",
    "results": {
      "skip": 0,
      "limit": 1,
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    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest Premium Plus Active Foam Whitening scope Sodium Fluoride SUCRALOSE POLOXAMER 407 BLUE 1 POLYSORBATE 80 SODIUM SACCHARIN CETYLPYRIDINIUM CHLORIDE TITANIUM DIOXIDE SODIUM HYDROXIDE XANTHAN GUM SORBITOL WATER HYDRATED SILICA SODIUM LAURYL SULFATE ALCOHOL SODIUM FLUORIDE FLUORIDE ION COCAMIDOPROPYL BETAINE GLYCERIN YELLOW 5 DISODIUM PYROPHOSPHATE"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, alcohol (0.7%), xanthan gum, sodium saccharin, glycerin, poloxamer 407, cocamidopropyl betaine, sucralose, polysorbate 80, cetylpyridinium chloride, titanium dioxide, blue 1, yellow 5"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 147 g Tube Carton Crest plus PREMIUM WITH FLIP CAP NET WT 5.2OZ (147 g) ANTICAVITY FLUORIDE TOOTHPASTE ACTIVE FOAM + WHITENING Long lasting fresh breath scope OUTLAST MINT WITH MOUTHWASH STRIPES label"
      ],
      "set_id": "55004d9d-eda7-a285-e063-6294a90ad4ca",
      "id": "55003edd-9f63-d73e-e063-6394a90a05c6",
      "effective_time": "20260624",
      "version": "1",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest Premium Plus Active Foam Whitening scope"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "84126-660"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "891775"
        ],
        "spl_id": [
          "55003edd-9f63-d73e-e063-6394a90a05c6"
        ],
        "spl_set_id": [
          "55004d9d-eda7-a285-e063-6294a90ad4ca"
        ],
        "package_ndc": [
          "84126-660-72",
          "84126-660-52",
          "84126-660-03"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}