{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-29",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Medi First Extra Strength Itch Relief Diphenhydramine, Zinc Acetate METHYLPARABEN POLYSORBATE 60 PROPYLPARABEN ZINC ACETATE ZINC CATION CARBOMER HOMOPOLYMER TYPE C CETYL ALCOHOL GLYCERIN DIPHENHYDRAMINE HYDROCHLORIDE DIPHENHYDRAMINE GLYCERYL MONOSTEARATE LIGHT MINERAL OIL STEARIC ACID"
      ],
      "spl_unclassified_section": [
        "Drug Facts Drug Facts"
      ],
      "active_ingredient": [
        "Active Ingredient Active Ingredient Diphenhydramine Hydrochloride 2% Zinc Acetate 0.1%"
      ],
      "purpose": [
        "Purpose Purpose Topical Analgesic Skin Protectant"
      ],
      "indications_and_usage": [
        "Uses Uses Temporary relievies pain and itching associated with: insect bites minor burns sunburn minor skin irritations minor cuts scrapes rashes due to poison ivy, poison oak and poison sumac Dries the oozing and weeping of poison ivy, poison oak, and poison sumac"
      ],
      "warnings": [
        "Warnings Warnings For external use only."
      ],
      "do_not_use": [
        "Do not use Do not use on large areas of the body with any other product containing diphenhydramine, even one taken by mouth"
      ],
      "ask_doctor": [
        "Ask a doctor before use Ask a doctor before use on chicken pox on measles"
      ],
      "stop_use": [
        "Stop use and ask a doctor if Stop use and ask a doctor if condition worsens or does not improve withn 7 days symptoms persist for more than 7 days or clear up and occur again within a few days"
      ],
      "keep_out_of_reach_of_children": [
        "Keep our of reach of children Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center immediately."
      ],
      "dosage_and_administration": [
        "Directions Directions do not use more than directed adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily for children under 2 years of age: do not use, consult a doctor"
      ],
      "other_safety_information": [
        "Other information Other information Store between 15°-30° *(59°-86°F) Lot No. & Exp Date: See box or crimp of tube."
      ],
      "inactive_ingredient": [
        "Inactive ingredients Inactive ingredients Carbomer homopolymer type C, cetyl alcohol, glycerin, glyceryl monostearate, light mineral oil, methyparaben, polysorbate 60, proplyparaben, purified water, stearic acid"
      ],
      "questions": [
        "Questions or comments? Questions or comments? Call 1-800-635-7680"
      ],
      "recent_major_changes": [
        ""
      ],
      "package_label_principal_display_panel": [
        "Principal Display Panel Medi ♥ First Topical Solutions healing made easy NDC #47682-865-29 Histamine Blocker Extra Strength Itch Relief Temporary relief from pain and itching caused by insect bites, minoir burns, sunburn, rashes due to poison ivy, oak, sumac and more *Compare to the Active Ingredients in Extra Strength Benadryl® Cream 58429 Anti-Itch Cream 1-29-26"
      ],
      "set_id": "54614e5b-8c72-d308-e063-6294a90a405d",
      "id": "54616303-c022-41d2-e063-6394a90a3273",
      "effective_time": "20260616",
      "version": "1",
      "openfda": {
        "application_number": [
          "M017"
        ],
        "brand_name": [
          "Medi First Extra Strength Itch Relief"
        ],
        "generic_name": [
          "DIPHENHYDRAMINE, ZINC ACETATE"
        ],
        "manufacturer_name": [
          "Unifirst First Aid Corporation"
        ],
        "product_ndc": [
          "47682-865"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "TOPICAL"
        ],
        "substance_name": [
          "ZINC ACETATE",
          "DIPHENHYDRAMINE HYDROCHLORIDE"
        ],
        "spl_id": [
          "54616303-c022-41d2-e063-6394a90a3273"
        ],
        "spl_set_id": [
          "54614e5b-8c72-d308-e063-6294a90a405d"
        ],
        "package_ndc": [
          "47682-865-29",
          "47682-865-70"
        ],
        "is_original_packager": [
          true
        ],
        "upc": [
          "0347682584290"
        ],
        "unii": [
          "FM5526K07A",
          "TC2D6JAD40"
        ]
      }
    }
  ]
}