{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-30",
    "results": {
      "skip": 0,
      "limit": 1,
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    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest Pro-Health Gum Restore Smooth Mint Cetylpyridinium chloride SODIUM BENZOATE WATER GLYCERIN ZINC LACTATE RED 33 SACCHARIN SODIUM SUCRALOSE POLOXAMER 407 CETYLPYRIDINIUM CHLORIDE CETYLPYRIDINIUM GREEN 3 BENZOIC ACID"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Cetylpyridinium chloride 0.07%"
      ],
      "purpose": [
        "Purpose Antigingivitis/Antiplaque"
      ],
      "indications_and_usage": [
        "Uses helps prevent and reduce plaque and gingivitis helps control plaque bacteria that contribute to the development of gingivitis and bleeding gums"
      ],
      "warnings": [
        "Warnings Ask a dentist if symptoms persist or condition worsens after regular use. Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "ask_doctor": [
        "Ask a dentist if symptoms persist or condition worsens after regular use."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions use after your normal brushing and flossing routine; rinse toothpaste from mouth prior to use adults and children 6 yrs. & older: Rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day do not swallow children 6 years to under 12 years of age: supervise use children under 6 years of age: do not use"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, glycerin, flavor, poloxamer 407, sodium benzoate, zinc lactate, sodium saccharin, sucralose, benzoic acid, red 33, green 3"
      ],
      "questions": [
        "Questions? 1-800-285-9139"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 1 L Bottle Label ALCOHOL FREE Crest PRO-HEALTH CPC ANTIGINGIVITIS/ANTIPLAQUE MOUTHWASH GUM RESTORE 24 HR PROTECTION WITH ADVANCED COOLING TECHNOLOGY Helps Reduce Gum Inflammation SMOOTH MINT 1 L (33.8 FL OZ) LABEL"
      ],
      "set_id": "4f6e3b36-e565-7d27-e063-6294a90ae5ac",
      "id": "4f6e3b36-e566-7d27-e063-6294a90ae5ac",
      "effective_time": "20260414",
      "version": "1",
      "openfda": {
        "application_number": [
          "M022"
        ],
        "brand_name": [
          "Crest Pro-Health Gum Restore Smooth Mint"
        ],
        "generic_name": [
          "CETYLPYRIDINIUM CHLORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "84126-649"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "ORAL"
        ],
        "substance_name": [
          "CETYLPYRIDINIUM CHLORIDE"
        ],
        "rxcui": [
          "1100924",
          "1251371"
        ],
        "spl_id": [
          "4f6e3b36-e566-7d27-e063-6294a90ae5ac"
        ],
        "spl_set_id": [
          "4f6e3b36-e565-7d27-e063-6294a90ae5ac"
        ],
        "package_ndc": [
          "84126-649-01"
        ],
        "is_original_packager": [
          true
        ],
        "upc": [
          "0037000558255"
        ],
        "unii": [
          "D9OM4SK49P"
        ]
      }
    }
  ]
}