{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-30",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest 3D White Advanced Arctic Fresh with Stain-Blasting Foam Sodium Fluoride XANTHAN GUM POLOXAMER 407 SODIUM LAURYL SULFATE FD&C BLUE NO. 1 POLYSORBATE 80 SORBITOL WATER TITANIUM DIOXIDE HYDRATED SILICA SACCHARIN SODIUM MICA COCAMIDOPROPYL BETAINE DISODIUM PYROPHOSPHATE SODIUM FLUORIDE FLUORIDE ION SODIUM HYDROXIDE"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, hydrated silica, sorbitol, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, xanthan gum, sodium saccharin, poloxamer 407, cocamidopropyl betaine, polysorbate 80, mica, titanium dioxide, blue 1"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 68 g Tube Carton CREST 3D WHITE ADVANCED ARCTIC FRESH WITH STAIN-BLASTING FOAM Whiter Teeth in 5 DAYS new wt 2.4 OZ (68 g) fluoride anticavity toothpaste enamel safe label"
      ],
      "set_id": "4ef4146d-6281-fe66-e063-6394a90a32c3",
      "id": "4f08260b-c544-87ed-e063-6394a90a3639",
      "effective_time": "20260409",
      "version": "3",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest 3D White Advanced Arctic Fresh with Stain-Blasting Foam"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "84126-628"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "891775"
        ],
        "spl_id": [
          "4f08260b-c544-87ed-e063-6394a90a3639"
        ],
        "spl_set_id": [
          "4ef4146d-6281-fe66-e063-6394a90a32c3"
        ],
        "package_ndc": [
          "84126-628-24",
          "84126-628-33",
          "84126-628-49",
          "84126-628-05",
          "84126-628-06",
          "84126-628-04"
        ],
        "is_original_packager": [
          true
        ],
        "upc": [
          "0030772125526"
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}