{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-28",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Colgate Deep Clean Fluoride SODIUM FLUORIDE SODIUM FLUORIDE FLUORIDE ION WATER SORBITOL HYDRATED SILICA POLYETHYLENE GLYCOL 600 POLOXAMER 407 SODIUM LAURYL SULFATE XANTHAN GUM COCAMIDOPROPYL BETAINE SODIUM PYROPHOSPHATE SACCHARIN SODIUM MICA FD&C BLUE NO. 1 TITANIUM DIOXIDE"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "Dist. by: COLGATE-PALMOLIVE COMPANY New York, NY 10022 U.S.A."
      ],
      "active_ingredient": [
        "Active ingredient Sodium Fluoride 0.24% (0.14% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warnings Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 years of age and older brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician children 2 to 6 years use only a pea sized amount and supervise child's brushing and rinsing (to minimize swallowing) children under 2 years ask a dentist or physician"
      ],
      "dosage_and_administration_table": [
        "<table width=\"60%\" styleCode=\"Noautorules\"><col width=\"30%\" align=\"left\" valign=\"top\"/><col width=\"70%\" align=\"left\" valign=\"top\"/><tbody><tr styleCode=\"Botrule\"><td styleCode=\"Rrule\">adults and children 2 years of age and older</td><td>brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician</td></tr><tr styleCode=\"Botrule\"><td styleCode=\"Rrule\">children 2 to 6 years</td><td>use only a pea sized amount and supervise child&apos;s brushing and rinsing (to minimize swallowing)</td></tr><tr><td styleCode=\"Rrule\">children under 2 years</td><td>ask a dentist or physician</td></tr></tbody></table>"
      ],
      "inactive_ingredient": [
        "Inactive ingredients Water, Sorbitol, Hydrated Silica, PEG-12, Poloxamer 407, Sodium Lauryl Sulfate, Flavor, Xanthan Gum, Cocamidopropyl Betaine, Tetrasodium Pyrophosphate, Sodium Saccharin, Mica, Blue 1, Titanium Dioxide."
      ],
      "questions": [
        "Questions? 1-800-468-6502"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 170 g Tube Carton Colgate ® Anticavity Fluoride Toothpaste WITH MICRO-FOAMING ACTION DEEP CLEAN PENETRATES BETWEEN TEETH FOR A RUSH OF CLEAN BRISK MINT ® NET WT 6.0 OZ (170 g) PRINCIPAL DISPLAY PANEL - 170 g Tube Carton"
      ],
      "set_id": "47e8e943-f4d5-40bc-8f79-ec9ea06125de",
      "id": "bf6afe2e-000d-4d81-8b5f-a0225a175398",
      "effective_time": "20260701",
      "version": "5",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Colgate Deep Clean Fluoride"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "Colgate-Palmolive Company"
        ],
        "product_ndc": [
          "35000-969"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "416783"
        ],
        "spl_id": [
          "bf6afe2e-000d-4d81-8b5f-a0225a175398"
        ],
        "spl_set_id": [
          "47e8e943-f4d5-40bc-8f79-ec9ea06125de"
        ],
        "package_ndc": [
          "35000-969-60",
          "35000-969-79",
          "35000-969-58"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}