{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-27",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "MYEVER Estriol Cream AQUA AVENA SATIVA (OAT) KERNEL OIL PALMITOYL TRIPEPTIDE-1 PALMITOYL TETRAPEPTIDE-7 CITRUS BIOFLAVONOIDS SODIUM BENZOATE ERYNGIUM MARITIMUM ROOT VITIS VINIFERA (GRAPE) SEED OIL SOY ISOFLAVONES CIMICIFUGA RACEMOSA ROOT ESTRIOL ESTRIOL POLYGONUM CUSPIDATUM ROOT SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL CRITHMUM MARITIMUM BUTYLENE GLYCOL PUNICA GRANATUM FRUIT JUICE MYRICETIN DIOSCOREA OPPOSITIFOLIA (WILD YAM) ROOT ASIATICOSIDE HYALURONIC ACID SODIUM HYALURONATE PALMITOYL PENTAPEPTIDE-4 TOCOPHEROL GLABRIDIN POTASSIUM SORBATE GINKGO BILOBA LEAF PUERARIA MONTANA VAR. LOBATA ROOT GLYCERIN COCO-GLUCOSIDE TRIFOLIUM PRATENSE (CLOVER) FLOWER PANAX GINSENG ROOT SQUALANE CAMELLIA SINENSIS LEAF"
      ],
      "active_ingredient": [
        "Active ingredient(s) Estriol 0.2%"
      ],
      "purpose": [
        "Purpose(s) Skin Protectant"
      ],
      "indications_and_usage": [
        "Uses Temporarily relieves external vulvar dryness Helps prevent and temporarily protects irritated skin."
      ],
      "warnings": [
        "Warnings For external use only. Do not use If you are pregnant or breast-feeding. On minors under 18 years of age. If you have a known sensitivity to estrogen or a hormone-related condition (e.g., breast cancer, endometriosis). On open wounds, swollen areas, rashes, or active infections. When using this product Avoid contact with eyes. Stop use and ask a doctor if A burning sensation, itching, or redness occurs and persists. Condition worsens or symptoms last more than 7 days."
      ],
      "do_not_use": [
        "Do not use If you are pregnant or breast-feeding. On minors under 18 years of age. If you have a known sensitivity to estrogen or a hormone-related condition (e.g., breast cancer, endometriosis). On open wounds, swollen areas, rashes, or active infections."
      ],
      "when_using": [
        "When using this product Avoid contact with eyes."
      ],
      "stop_use": [
        "Stop use and ask a doctor if A burning sensation, itching, or redness occurs and persists. Condition worsens or symptoms last more than 7 days."
      ],
      "pregnancy_or_breast_feeding": [
        "Pregnancy or breast feeding section Do not use if pregnant or breast-feeding."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children In case of accidental ingestion, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions Cleanse hands and the external vulvar area with a mild, soap-free cleanser and pat dry. Apply a pea-sized amount (approx. 0.3 g) to the fingertip. Gently apply and massage into the dry areas of the vulva in a circular motion until fully absorbed. After an initial treatment of 2-3 weeks, reduce frequency to a maintenance level (e.g., twice a week)."
      ],
      "other_safety_information": [
        "Other information Store in a cool, dry place below 25°C (77°F). Avoid direct sunlight and high humidity. Use within 6 months after opening."
      ],
      "inactive_ingredient": [
        "Inactive ingredients AQUA, BUTYLENE GLYCOL, GLYCERIN, VITIS VINIFERA (GRAPE) SEED OIL, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, SQUALANE, COCO-GLUCOSIDE, TOCOPHEROL, ASIATICOSIDE, SOY ISOFLAVONES, DIOSCOREA OPPOSITIFOLIA (WILD YAM) ROOT, POLYGONUM CUSPIDATUM ROOT, PUERARIA MONTANA VAR. LOBATA ROOT, HYALURONIC ACID, SODIUM HYALURONATE, SODIUM BENZOATE, POTASSIUM SORBATE, CIMICIFUGA RACEMOSA ROOT, PUNICA GRANATUM FRUIT JUICE, TRIFOLIUM PRATENSE (CLOVER) FLOWER, CAMELLIA SINENSIS LEAF EXTRACT, PANAX GINSENG ROOT, AVENA SATIVA (OAT) KERNEL OIL, PALMITOYL PENTAPEPTIDE-4, PALMITOYL TRIPEPTIDE-1, PALMITOYL TETRAPEPTIDE-7, CITRUS BIOFLAVONOIDS, GLABRIDIN, GINKGO BILOBA LEAF, MYRICETIN, CRITHMUM MARITIMUM, ERYNGIUM MARITIMUM ROOT"
      ],
      "questions": [
        "Questions or comments? 934-935-7135 / Rangelcervel824@gmail.com"
      ],
      "package_label_principal_display_panel": [
        "Box Front Panel MYEVER INTIMATE ESTRIOL CREAM Package"
      ],
      "set_id": "3ed85485-a441-4c05-e063-6394a90afef5",
      "id": "4de4ae83-bd2d-b31a-e063-6394a90a3e1a",
      "effective_time": "20260325",
      "version": "2",
      "openfda": {
        "application_number": [
          "M016"
        ],
        "brand_name": [
          "MYEVER"
        ],
        "generic_name": [
          "ESTRIOL CREAM"
        ],
        "manufacturer_name": [
          "Hubei Redrui Building Materials Co., Ltd."
        ],
        "product_ndc": [
          "87066-5915"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "TOPICAL"
        ],
        "substance_name": [
          "ESTRIOL"
        ],
        "spl_id": [
          "4de4ae83-bd2d-b31a-e063-6394a90a3e1a"
        ],
        "spl_set_id": [
          "3ed85485-a441-4c05-e063-6394a90afef5"
        ],
        "package_ndc": [
          "87066-5915-1"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "FB33469R8E"
        ]
      }
    }
  ]
}