{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-29",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "effective_time": "20180724",
      "inactive_ingredient": [
        "Inactive ingredients water, hydrated silica, glycerin, sorbitol, PVM/MA copolymer, sodium lauryl sulfate, flavor, cellulose gum, sodium hydroxide, propylene glycol, carrageenan, sodium saccharin, titanium dioxide"
      ],
      "purpose": [
        "Purpose Anticavity Antigingivitis"
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of the reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "warnings": [
        "Warnings Keep out of the reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away. Ask a dentist before use if you have bleeding or redness lasting more than 2 weeks pain, swelling, pus, loose teeth, or more spacing between teeth These may be signs of periodontitis, a serious form of gum disease."
      ],
      "questions": [
        "Questions or comments? Call toll-free 1-800-468-6502"
      ],
      "spl_product_data_elements": [
        "Colgate Total Advance Whitening Sodium Fluoride and Triclosan WATER HYDRATED SILICA GLYCERIN SORBITOL BUTYL ESTER OF METHYL VINYL ETHER/MALEIC ANHYDRIDE COPOLYMER (125000 MW) SODIUM LAURYL SULFATE SODIUM HYDROXIDE PROPYLENE GLYCOL SACCHARIN SODIUM CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED FORM TITANIUM DIOXIDE CARRAGEENAN SODIUM FLUORIDE FLUORIDE ION TRICLOSAN TRICLOSAN"
      ],
      "ask_doctor": [
        "Ask a dentist before use if you have bleeding or redness lasting more than 2 weeks pain, swelling, pus, loose teeth, or more spacing between teeth These may be signs of periodontitis, a serious form of gum disease."
      ],
      "openfda": {},
      "version": "2",
      "dosage_and_administration": [
        "Directions supervise children as necessary until capable of using without supervision. adults and children 6 years of age and older brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or a physician children under 12 years instruct in good brushing and rinsing habits (to minimize swallowing) children under 6 years do not use unless directed by a dentist or a physician Antiplaque and antigingivitis use not proven in children."
      ],
      "spl_unclassified_section": [
        "Dist. by: COLGATE-PALMOLIVE COMPANY New York, NY 10022 Made in U.S.A. www.colgatetotal.com"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 226 g Tube Helps Prevent Cavities • Gingivitis • Plaque Colgate ® Total ® Anticavity Fluoride and Antigingivitis Toothpaste ADVANCED WHITENING PASTE HELPS REMOVE & PREVENT STAINS* ADA ACCEPTED American Dental Association ® NET WT 8.0 OZ (226 g) Principal Display Panel - 226 g Tube",
        "PRINCIPAL DISPLAY PANEL - 226 g carton Helps Prevent Cavities • Gingivitis • Plaque Colgate ® Total® Anticavity Fluoride and Antigingivitis Toothpaste ADVANCED WHITENING PASTE HELPS REMOVE & PREVENT STAINS* ADA ACCEPTED American Dental Association ® NET WT 8.0 OZ (226 g) Principal Display Panel - 226 g carton"
      ],
      "indications_and_usage": [
        "Uses aids in the prevention of: cavities plaque gingivitis"
      ],
      "set_id": "334a3704-d08f-0a85-e054-00144ff8d46c",
      "id": "71c08847-9679-ff89-e053-2a95a90ad9cc",
      "active_ingredient": [
        "Active ingredients Sodium fluoride 0.24% (0.15% w/v fluoride ion) Triclosan 0.30%"
      ],
      "dosage_and_administration_table": [
        "<table width=\"70%\"> <col width=\"35%\" align=\"left\" valign=\"top\"/> <col width=\"65%\" align=\"left\" valign=\"top\"/> <tbody> <tr styleCode=\"TopRule\"> <td styleCode=\"Rrule BotRule\">adults and children 6 years of age and older</td> <td styleCode=\"BotRule\">brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or a physician</td> </tr> <tr styleCode=\"BotRule\"> <td styleCode=\"Rrule\">children under 12 years</td> <td>instruct in good brushing and rinsing habits   (to minimize swallowing) </td> </tr> <tr styleCode=\"BotRule\"> <td styleCode=\"Rrule\">children under 6 years</td> <td>do not use unless directed by a dentist or a physician</td> </tr> </tbody> </table>"
      ]
    }
  ]
}