{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-28",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "effective_time": "20160520",
      "inactive_ingredient": [
        "Inactive ingredients Hydrated silica, water, glycerin, sorbitol, PVM/MA copolymer, sodium lauryl sulfate, cellulose gum, flavor, sodium hydroxide, carrageenan, propylene glycol, sodium saccharin, mica, titanium dioxide, FD&C blue no. 1, D&C yellow no. 10"
      ],
      "purpose": [
        "Active ingredients Purpose Sodium Fluoride 0.24% (0.15% w/v fluoride ion) Anticavity Triclosan 0.30% Antigingivitis"
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of the reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "warnings": [
        "Warnings Keep out of the reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away. Ask a dentist before use if you have bleeding or redness lasting more than 2 weeks pain, swelling, pus, loose teeth, or more spacing between teeth These may be signs of periodontitis, a serious form of gum disease."
      ],
      "questions": [
        "Questions or comments? Call toll-free 1-800-468-6502"
      ],
      "spl_product_data_elements": [
        "Colgate Total Advanced Whitening Sodium Fluoride and Triclosan WATER HYDRATED SILICA GLYCERIN SORBITOL BUTYL ESTER OF METHYL VINYL ETHER/MALEIC ANHYDRIDE COPOLYMER (125000 MW) SODIUM LAURYL SULFATE SODIUM HYDROXIDE PROPYLENE GLYCOL SACCHARIN SODIUM CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED FORM MICA TITANIUM DIOXIDE CARRAGEENAN FD&C BLUE NO. 1 D&C YELLOW NO. 10 SODIUM FLUORIDE FLUORIDE ION TRICLOSAN TRICLOSAN"
      ],
      "ask_doctor": [
        "Ask a dentist before use if you have bleeding or redness lasting more than 2 weeks pain, swelling, pus, loose teeth, or more spacing between teeth These may be signs of periodontitis, a serious form of gum disease."
      ],
      "openfda": {},
      "version": "1",
      "dosage_and_administration": [
        "Directions supervise children as necessary until capable of using without supervision. adults and children 6 years of age and older brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or a physician children under 12 years instruct in good brushing and rinsing habits (to minimize swallowing) children under 6 years do not use unless directed by a dentist or a physician Antiplaque and antigingivitis use not proven in children."
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "Dist. by: COLGATE-PALMOLIVE COMPANY New York, NY 10022"
      ],
      "active_ingredient_table": [
        "<table width=\"55%\"> <col width=\"60%\" align=\"left\" valign=\"top\"/> <col width=\"40%\" align=\"right\" valign=\"top\"/> <thead> <tr> <th> <content styleCode=\"italics\">Active ingredients</content> </th> <th> <content styleCode=\"italics\">Purpose</content> </th> </tr> </thead> <tbody> <tr> <td>Sodium Fluoride 0.24% (0.15% w/v fluoride ion)</td> <td>Anticavity</td> </tr> <tr> <td>Triclosan 0.30%</td> <td>Antigingivitis</td> </tr> </tbody> </table>"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 164 g Tube Carton BETTER WHITENING* Colgate ® Anticavity Fluoride and Antigingivitis Toothpaste Total ® ADVANCED WHITENING NET WT 5.8 OZ (164 g) ADVANCED STAIN REMOVAL* FOR A BEAUTIFUL SMILE ✓ CAVITIES ✓ PLAQUE ✓ GINGIVITIS ✓ ENAMEL ✓ TARTAR ✓ BREATH ✓ WHITENS Gel Principal Display Panel - 164 g Tube Carton"
      ],
      "indications_and_usage": [
        "Uses aids in the prevention of: cavities plaque gingivitis"
      ],
      "set_id": "334a0715-ebdd-6a7c-e054-00144ff8d46c",
      "id": "334a8671-a4cc-35d4-e054-00144ff88e88",
      "purpose_table": [
        "<table width=\"55%\"> <col width=\"60%\" align=\"left\" valign=\"top\"/> <col width=\"40%\" align=\"right\" valign=\"top\"/> <thead> <tr> <th> <content styleCode=\"italics\">Active ingredients</content> </th> <th> <content styleCode=\"italics\">Purpose</content> </th> </tr> </thead> <tbody> <tr> <td>Sodium Fluoride 0.24% (0.15% w/v fluoride ion)</td> <td>Anticavity</td> </tr> <tr> <td>Triclosan 0.30%</td> <td>Antigingivitis</td> </tr> </tbody> </table>"
      ],
      "active_ingredient": [
        "Active ingredients Purpose Sodium Fluoride 0.24% (0.15% w/v fluoride ion) Anticavity Triclosan 0.30% Antigingivitis"
      ],
      "dosage_and_administration_table": [
        "<table width=\"65%\" styleCode=\"Noautorules\"> <col width=\"40%\" align=\"left\" valign=\"top\"/> <col width=\"60%\" align=\"left\" valign=\"top\"/> <tbody> <tr> <td styleCode=\"Botrule Rrule\">adults and children 6 years of age and older</td> <td styleCode=\"Botrule\">brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or a physician</td> </tr> <tr styleCode=\"Botrule\"> <td styleCode=\"Rrule\">children under 12 years</td> <td>instruct in good brushing and rinsing habits (to minimize swallowing)</td> </tr> <tr> <td styleCode=\"Rrule\">children under 6 years</td> <td>do not use unless directed by a dentist or a physician</td> </tr> </tbody> </table>"
      ]
    }
  ]
}