{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-30",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "effective_time": "20160517",
      "inactive_ingredient": [
        "Inactive ingredients water, glycerin, propylene glycol, sorbitol, poloxamer 407, flavor, potassium sorbate, citric acid, sodium saccharin, FD&C blue no. 1"
      ],
      "purpose": [
        "Purpose Antigingivitis/antiplaque"
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "warnings": [
        "Warnings Ask a dentist if condition persists or worsens after regular use. Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "questions": [
        "Questions? 1-800-468-6502"
      ],
      "spl_product_data_elements": [
        "Colgate Total Advanced Pro-Shield Peppermint Blast CETYLPYRIDINIUM CHLORIDE WATER GLYCERIN PROPYLENE GLYCOL SORBITOL POLOXAMER 407 POTASSIUM SORBATE SACCHARIN SODIUM LEVOMENTHOL ANHYDROUS CITRIC ACID FD&C BLUE NO. 1 CETYLPYRIDINIUM CHLORIDE CETYLPYRIDINIUM"
      ],
      "ask_doctor": [
        "Ask a dentist if condition persists or worsens after regular use."
      ],
      "openfda": {},
      "version": "1",
      "dosage_and_administration": [
        "Directions adults and children 12 years of age and older rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day. Do not swallow. children 6 years to under 12 years of age supervise use children under 6 years of age do not use"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "Dist. by: COLGATE-PALMOLIVE COMPANY New York, NY 10022"
      ],
      "storage_and_handling": [
        "Other Information this rinse is not intended to replace brushing or flossing store at 59°F to 77°F keep from freezing"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 1 L Bottle Label ALCOHOL FREE Colgate ® Antigingivitis/Antiplaque Mouthwash Total ® ADVANCED PRO-SHIELD ™ 12-HR Protection Against Germs* KILLS 99% OF GERMS ON CONTACT SIGNIFICANTLY REDUCES PLAQUE HELPS PREVENT GINGIVITIS NO BURN OF ALCOHOL FRESHENS BREATH PEPPERMINT BLAST ™ 33.8 FL OZ (1.05 QT) 1 L P9892866 PRINCIPAL DISPLAY PANEL - 1 L Bottle Label"
      ],
      "indications_and_usage": [
        "Uses helps prevent and reduce plaque and gingivitis"
      ],
      "set_id": "330d04d2-1933-163c-e054-00144ff88e88",
      "id": "330d04d2-1934-163c-e054-00144ff88e88",
      "active_ingredient": [
        "Active ingredient Cetylpyridinium chloride 0.075%"
      ],
      "dosage_and_administration_table": [
        "<table width=\"75%\" styleCode=\"Noautorules\"> <col width=\"30%\" align=\"left\" valign=\"top\"/> <col width=\"70%\" align=\"left\" valign=\"top\"/> <tbody> <tr styleCode=\"Botrule\"> <td styleCode=\"Rrule\">adults and children 12 years of age and older</td> <td>rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day. Do not swallow.</td> </tr> <tr styleCode=\"Botrule\"> <td styleCode=\"Rrule\">children 6 years to under 12 years of age</td> <td>supervise use</td> </tr> <tr> <td styleCode=\"Rrule\">children under 6 years of age</td> <td>do not use</td> </tr> </tbody> </table>"
      ]
    }
  ]
}