{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-30",
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  "results": [
    {
      "spl_product_data_elements": [
        "KIDS Crest Advanced Sugar and Bacteria Shield Stannous Fluoride GLYCERIN COCAMIDOPROPYL BETAINE STANNOUS CHLORIDE WATER HYDRATED SILICA CARRAGEENAN SODIUM GLUCONATE XANTHAN GUM SODIUM LAURYL SULFATE SORBITOL SODIUM HYDROXIDE SUCRALOSE TITANIUM DIOXIDE SODIUM CITRATE STANNOUS FLUORIDE FLUORIDE ION SACCHARIN SODIUM"
      ],
      "active_ingredient": [
        "Drug Facts Active ingredient Stannous fluoride 0.454% (0.15% w/v fluoride ion)"
      ],
      "purpose": [
        "Purposes Anticavity, antigingivitis toothpaste"
      ],
      "indications_and_usage": [
        "Use • aids in the prevention of cavities • helps prevent gingivitis • helps interfere with the harmful effects of plaque associated with gingivitis • helps control plaque bacteria that contribute to the development of gingivitis"
      ],
      "warnings": [
        "Warning Keep out of reach of children under 6 yrs. of age . If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age . If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions • adults and children 6 yrs. of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. • do not swallow • supervise children's brushing until good habits are established • children under 6 yrs. of age: ask a dentist"
      ],
      "warnings_and_cautions": [
        "Other information • products containing stannous fluoride may produce surface staining of the teeth • adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist • this Crest is specially formulated to help prevent staining • see your dentist regularly Inactive ingredients"
      ],
      "inactive_ingredient": [
        "glycerin, water, sorbitol, hydrated silica, sodium lauryl sulfate, sodium citrate, sodium gluconate, carrageenan, xanthan gum, flavor, sodium saccharin, cocamidopropyl betaine, sodium hydroxide, stannous chloride, sucralose, titanium dioxide"
      ],
      "questions": [
        "Questions? 1-800-594-4158"
      ],
      "spl_unclassified_section": [
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "recent_major_changes": [
        ""
      ],
      "package_label_principal_display_panel": [
        "Crest Kids Advanced Sugar & Bacteria Shield OUR MOST ADVANCED KID'S FORMULA KID'S Crest® ADVANCED FLUORIDE TOOTHPASTE FOR ANTICAVITY AND ANTIGINGIVITIS ADA ACCEPTED AMERICAN DENTAL ASSOCIATION NET WT 4.1 OZ (116 g) 6+ yrs sugar & Bacteria SHIELD 2-IN-1 Cavity Protection System STRAWBERRY Label"
      ],
      "set_id": "2f371af0-a2d4-25a6-e063-6394a90a923d",
      "id": "47e5406b-31c0-aec9-e063-6294a90ac186",
      "effective_time": "20260108",
      "version": "2",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "KIDS Crest Advanced Sugar and Bacteria Shield"
        ],
        "generic_name": [
          "STANNOUS FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "84126-612"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "STANNOUS FLUORIDE"
        ],
        "rxcui": [
          "416784"
        ],
        "spl_id": [
          "47e5406b-31c0-aec9-e063-6294a90ac186"
        ],
        "spl_set_id": [
          "2f371af0-a2d4-25a6-e063-6394a90a923d"
        ],
        "package_ndc": [
          "84126-612-85",
          "84126-612-41",
          "84126-612-03"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "3FTR44B32Q"
        ]
      }
    }
  ]
}