{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-29",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest Pro-Health Advanced Multi-Protection Sodium Fluoride WATER GLYCERIN CETYLPYRIDINIUM CHLORIDE SACCHARIN SODIUM PHOSPHORIC ACID METHYLPARABEN SUCRALOSE POLOXAMER 407 PROPYLPARABEN SODIUM PHOSPHATE, DIBASIC, ANHYDROUS FD&C BLUE NO. 1 SODIUM FLUORIDE FLUORIDE ION"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium Fluoride 0.02% (0.01% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity"
      ],
      "indications_and_usage": [
        "Use Aids in the prevention of dental cavities"
      ],
      "warnings": [
        "Warning Keep out of reach of children. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions Adults and children 6 years & older: Use twice a day after brushing your teeth with a toothpaste. Vigorously swish 10 mL (2 teaspoonfuls) of rinse between your teeth for 1 minute and then spit out. Do not swallow the rinse. Do not eat or drink for 30 minutes after rinsing. Instruct children under 12 years of age in good rinsing habits (to minimize swallowing). Supervise children as necessary until capable of using without supervision. Children under 6 years of age: consult a dentist or doctor."
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, glycerin, flavor, poloxamer 407, cetylpyridinium chloride, sodium saccharin, phosphoric acid, methylparaben, sucralose, propylparaben, disodium phosphate, blue 1"
      ],
      "questions": [
        "Questions? 1-800-862-7442"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 1 L Bottle Label + FLUORIDE CREST PRO-HEALTH ADVANCED ANTICAVITY FLUORIDE MOUTHWASH MULTI-PROTECTION ALCOHOL FREE IMPORTANT: Read directions for proper use. KILLS BAD BREATH GERMS REBUILDS WEAKENED ENAMEL PROTECTS AGAINST CAVITIES CLEANS WHOLE MOUTH FRESHENS BREATH STRENGTHENS TEETH 1L 33.8 FL OZ) Label"
      ],
      "set_id": "1cfc5b61-c8e5-943d-e063-6394a90a890b",
      "id": "4f6d6170-5659-37be-e063-6294a90ae93c",
      "effective_time": "20260414",
      "version": "4",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest Pro-Health Advanced Multi-Protection"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "84126-600"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "ORAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "313029"
        ],
        "spl_id": [
          "4f6d6170-5659-37be-e063-6294a90ae93c"
        ],
        "spl_set_id": [
          "1cfc5b61-c8e5-943d-e063-6394a90a890b"
        ],
        "package_ndc": [
          "84126-600-50",
          "84126-600-10",
          "84126-600-02"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}