{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-26",
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  "results": [
    {
      "spl_product_data_elements": [
        "Differin Daily Deep Cleanser with BPO benzoyl peroxide Benzoyl Peroxide Benzoyl Peroxide Carboxypolymethylene Lauryl Methacrylate/glycol Dimethacrylate Crosspolymer Sodium C14-16 Olefin Sulfonate Sodium Hydroxide Water Glycerin 051803-P56842-1-Differin-Daily-Deep-Cleanser-4oz-Carton"
      ],
      "active_ingredient": [
        "Active Ingredients Benzoyl Peroxide 5%"
      ],
      "purpose": [
        "Purpose Acne treatment"
      ],
      "indications_and_usage": [
        "Uses For the treatment of acne"
      ],
      "warnings": [
        "Warnings For external use only. When using this product ■ skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. ■ avoid unnecessary sun exposure and use a sunscreen ■ avoid contact with the eyes, lips, and mouth ■ avoid contact with hair and dyed fabrics, which may be bleached by this product ■ skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. Do not use if you ■ Have very sensitive skin ■ Are sensitive to benzoyl peroxide Stop use and ask a doctor if ■ Irritation becomes severe"
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions ■ Wet face. Gently massage all over face for about 20 – 30 seconds, avoiding the eye area. Rinse thoroughly and pat dry. ■ Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor. ■ If bothersome dryness or peeling occurs, reduce application to once a day or every other day. ■ If going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor."
      ],
      "inactive_ingredient": [
        "Inactive Ingredients Carbomer, Glycerin, Lauryl Methacrylate/Glycol Dimethacrylate Crosspolymer, Sodium C14-16 Olefin Sulfonate, Sodium Hydroxide, Water"
      ],
      "storage_and_handling": [
        ""
      ],
      "questions": [
        "Questions or comments? 1-866-735-4137",
        "Distributed by: Galderma Laboratories, L.P. Dallas, TX 75201 USA All trademarks are the property of their respective owners Made in Canada www.differin.com"
      ],
      "package_label_principal_display_panel": [
        "Principle Display Panel - 4 FL OZ carton 5% Benzoyl Peroxide DIFFERIN ® CLEANSE Daily DEEP CLEANSER Benzoyl Peroxide 5% Acne Treatment Treats acne and helps prevent future breakouts Oil-absorbing Formulated for sensitive skin 4 FL OZ (118 mL) P56842-1"
      ],
      "set_id": "192b231b-51f1-457c-9a82-ef75671c0d34",
      "id": "24a54860-8467-4a81-85c7-2d07b17be1fc",
      "effective_time": "20231211",
      "version": "5",
      "openfda": {
        "application_number": [
          "M006"
        ],
        "brand_name": [
          "Differin Daily Deep Cleanser with BPO"
        ],
        "generic_name": [
          "BENZOYL PEROXIDE"
        ],
        "manufacturer_name": [
          "Galderma Laboratories, L.P."
        ],
        "product_ndc": [
          "0299-4606"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "TOPICAL"
        ],
        "substance_name": [
          "BENZOYL PEROXIDE"
        ],
        "rxcui": [
          "308696"
        ],
        "spl_id": [
          "24a54860-8467-4a81-85c7-2d07b17be1fc"
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        "spl_set_id": [
          "192b231b-51f1-457c-9a82-ef75671c0d34"
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        "package_ndc": [
          "0299-4606-00"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "W9WZN9A0GM"
        ]
      }
    }
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}