{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-30",
    "results": {
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  "results": [
    {
      "spl_product_data_elements": [
        "Proactivplus Smoothing BHA Cleanser SALICYLIC ACID WATER GLYCERIN DIMETHICONE ETHYLHEXYLGLYCERIN GLYCOLIC ACID SODIUM HYDROXIDE PHENOXYETHANOL PARAFFIN SALICYLIC ACID SALICYLIC ACID GLYCERYL MONOSTEARATE XANTHAN GUM HYDROGENATED PALM GLYCERIDES CITRATE CETOSTEARYL ALCOHOL PROPANEDIOL PEG-100 STEARATE POLYSORBATE 20 COCO-GLUCOSIDE ALOE VERA LEAF AMMONIUM ACRYLOYLDIMETHYLTAURATE, DIMETHYLACRYLAMIDE, LAURYL METHACRYLATE AND LAURETH-4 METHACRYLATE COPOLYMER, TRIMETHYLOLPROPANE TRIACRYLATE CROSSLINKED (45000 MPA.S) TERT-BUTYL ALCOHOL GLYCERYL OLEATE TOCOPHEROL CETYL ALCOHOL CITRIC ACID MONOHYDRATE"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "Distributed by Alchemee LLC, Hawthorne, NY 10532 Made in the USA of Foreign and Domestic Components Questions? 1-800-950-4695 • proactiv.com • Proactiv is a registered trademark of Taro Pharmaceuticals U.S.A., Inc."
      ],
      "active_ingredient": [
        "Active ingredient Salicylic Acid 1%"
      ],
      "purpose": [
        "Purpose Acne treatment"
      ],
      "indications_and_usage": [
        "Use for the management of acne"
      ],
      "warnings": [
        "Warnings For external use only When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "when_using": [
        "When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions Sensitivity Test for a New User. Apply product sparingly to one or two small affected areas during the first 3 days. If no discomfort occurs, follow the directions stated below. cover the entire affected area with a thin layer and rinse thoroughly one to three times daily because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor if bothersome dryness or peeling occurs, reduce application to once a day or every other day if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor."
      ],
      "inactive_ingredient": [
        "Inactive ingredients Water, Cetearyl Alcohol, Glycerin, Cetyl Alcohol, Propanediol, Paraffin, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Polysorbate 20, Xanthan Gum, Phenoxyethanol, Coco-Glucoside, Glyceryl Oleate, Sodium Hydroxide, Polyacrylate Crosspolymer-6, Ethylhexylglycerin, Citric Acid, Aloe Barbadensis Leaf Juice, t-Butyl Alcohol, Tocopherol, Hydrogenated Palm Glycerides Citrate."
      ],
      "questions": [
        "Questions or comments? 1-800-950-4695"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 60 mL Carton proactiv + Smoothing BHA Cleanser acne treatment 1% salicylic acid 6 FL. OZ. (177.4 mL) image 1"
      ],
      "set_id": "14b9a54c-9993-385e-e063-6394a90a27de",
      "id": "47d2963e-06df-c8ac-e063-6394a90a3738",
      "effective_time": "20260107",
      "version": "3",
      "openfda": {
        "application_number": [
          "M006"
        ],
        "brand_name": [
          "Proactivplus Smoothing BHA Cleanser"
        ],
        "generic_name": [
          "SALICYLIC ACID"
        ],
        "manufacturer_name": [
          "Alchemee, LLC"
        ],
        "product_ndc": [
          "11410-216"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "TOPICAL"
        ],
        "substance_name": [
          "SALICYLIC ACID"
        ],
        "rxcui": [
          "1038982"
        ],
        "spl_id": [
          "47d2963e-06df-c8ac-e063-6394a90a3738"
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        "spl_set_id": [
          "14b9a54c-9993-385e-e063-6394a90a27de"
        ],
        "package_ndc": [
          "11410-216-01",
          "11410-216-02"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "O414PZ4LPZ"
        ]
      }
    }
  ]
}