{ "meta": { "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.", "terms": "https://open.fda.gov/terms/", "license": "https://open.fda.gov/license/", "last_updated": "2026-08-11", "results": { "skip": 0, "limit": 1, "total": 1 } }, "results": [ { "spl_product_data_elements": [ "Pyrogenium Combination 9239 Pyrogenium Combination ASCORBIC ACID ASCORBIC ACID CONIUM MACULATUM FLOWERING TOP CONIUM MACULATUM FLOWERING TOP SOLANUM DULCAMARA WHOLE SOLANUM DULCAMARA WHOLE ECHINACEA ANGUSTIFOLIA WHOLE ECHINACEA ANGUSTIFOLIA WHOLE HORSE CHESTNUT HORSE CHESTNUT ANTIMONY POTASSIUM TARTRATE ANTIMONY CATION (3+) PROTORTONIA CACTI PROTORTONIA CACTI GALIUM APARINE WHOLE GALIUM APARINE WHOLE GENTIANA LUTEA ROOT GENTIANA LUTEA ROOT GERANIUM ROBERTIANUM WHOLE GERANIUM ROBERTIANUM WHOLE LACTIC ACID, DL- LACTIC ACID, DL- PULSATILLA MONTANA WHOLE PULSATILLA MONTANA WHOLE SULFUR SULFUR ANHYDROUS DIBASIC CALCIUM PHOSPHATE ANHYDROUS DIBASIC CALCIUM PHOSPHATE FERROSOFERRIC PHOSPHATE FERROSOFERRIC PHOSPHATE BOS TAURUS HYPOTHALAMUS BOS TAURUS HYPOTHALAMUS BEEF LIVER BEEF LIVER BOS TAURUS LYMPH VESSEL BOS TAURUS LYMPH VESSEL SUS SCROFA BONE MARROW SUS SCROFA BONE MARROW BOS TAURUS SPLEEN BOS TAURUS SPLEEN CORTISONE ACETATE CORTISONE BEEF KIDNEY BEEF KIDNEY MERCURIUS SOLUBILIS MERCURIUS SOLUBILIS THYROID, UNSPECIFIED THYROID, UNSPECIFIED BARIUM CARBONATE BARIUM CATION SCABIES LESION LYSATE (HUMAN) SCABIES LESION LYSATE (HUMAN) BOS TAURUS TONSIL BOS TAURUS TONSIL RANCID BEEF RANCID BEEF ALCOHOL WATER" ], "active_ingredient": [ "ACTIVE INGREDIENTS Ascorbicum acidum 3X Conium maculatum 4X Dulcamara 4X Echinacea angustifolia 4X Aesculus hippocastanum 6X Antimonium tartaricum 6X Coccus cacti 6X Galium aparine 6X Gentiana lutea 6X Geranium robertianum 6X L(+) Lacticum acidum 6X Pulsatilla 6X Sulphur 8X Calcarea phosphorica 10X Ferrum phosphoricum 10X Hypothalamus 10X Liver 10X Lymph 10X Medulla ossis 10X Spleen 10X Cortisone aceticum 13X Kidney 13X Mercurius solubilis 13X Thyroid 13X Baryta carbonica 28X Psorinum 28X Tonsils 28X Pyrogenium 198X" ], "questions": [ "QUESTIONS Professional Formulas PO Box 2034 Lake Oswego, OR 97035" ], "indications_and_usage": [ "INDICATIONS For the temporary relief of flu-like symptoms such as low grade fever, chills, muscle aches, congestion, occasional headache, or fatigue.*" ], "purpose": [ "*Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated." ], "warnings": [ "WARNINGS Persistent symptoms may be a sign of a serious condition. If symptoms persist or are accompanied by a fever, rash, or persistent headache, consult a doctor. Keep out of the reach of children. In case of overdose, get medical help or contact a poison control center right away. If pregnant or breastfeeding, ask a healthcare professional before use. Keep out of the reach of children. If pregnant or breastfeeding, ask a healthcare professional before use." ], "keep_out_of_reach_of_children": [ "Keep out of the reach of children." ], "pregnancy_or_breast_feeding": [ "If pregnant or breastfeeding, ask a healthcare professional before use." ], "dosage_and_administration": [ "DIRECTIONS Place drops under tongue 30 minutes before/after meals. Adults and children 12 years and over: Take 10 drops up to 3 times per day. Consult a physician for use in children under 12 years of age." ], "other_safety_information": [ "OTHER INFORMATION Tamper resistant. If seal is broken, do not use. After opening, close container tightly and store at room temperature away from heat." ], "inactive_ingredient": [ "INACTIVE INGREDIENTS 40% ethanol, purified water." ], "package_label_principal_display_panel": [ "LABEL Est 1985 Professional Formulas Complementary Health Pyrogenium Combination Homeopathic Remedy 1 FL. OZ. (29.5 mL) Label image" ], "set_id": "8b869987-bfd2-4451-a2a8-ce3a92e201f2", "id": "0fc86c8b-c6a0-4f1c-b081-b329bc8dfecc", "effective_time": "20260108", "version": "2", "openfda": { "brand_name": [ "Pyrogenium Combination 9239" ], "generic_name": [ "PYROGENIUM COMBINATION" ], "manufacturer_name": [ "Professional Complementary Health Formulas" ], "product_ndc": [ "63083-9239" ], "product_type": [ "HUMAN OTC DRUG" ], "route": [ "ORAL" ], "substance_name": [ "ASCORBIC ACID", "CONIUM MACULATUM FLOWERING TOP", "SOLANUM DULCAMARA WHOLE", "ECHINACEA ANGUSTIFOLIA WHOLE", "HORSE CHESTNUT", "ANTIMONY POTASSIUM TARTRATE", "PROTORTONIA CACTI", "GALIUM APARINE WHOLE", "GENTIANA LUTEA ROOT", "GERANIUM ROBERTIANUM WHOLE", "LACTIC ACID, DL-", "PULSATILLA MONTANA WHOLE", "SULFUR", "ANHYDROUS DIBASIC CALCIUM PHOSPHATE", "FERROSOFERRIC PHOSPHATE", "BOS TAURUS HYPOTHALAMUS", "BEEF LIVER", "BOS TAURUS LYMPH VESSEL", "SUS SCROFA BONE MARROW", "BOS TAURUS SPLEEN", "CORTISONE ACETATE", "BEEF KIDNEY", "MERCURIUS SOLUBILIS", "THYROID, UNSPECIFIED", "BARIUM CARBONATE", "SCABIES LESION LYSATE (HUMAN)", "BOS TAURUS TONSIL", "RANCID BEEF" ], "spl_id": [ "0fc86c8b-c6a0-4f1c-b081-b329bc8dfecc" ], "spl_set_id": [ "8b869987-bfd2-4451-a2a8-ce3a92e201f2" ], "package_ndc": [ "63083-9239-1" ], "is_original_packager": [ true ], "nui": [ "N0000193618", "M0001797", "N0000185371", "N0000175629", "N0000184306", "M0000728", "M0006342", "N0000185017" ], "pharm_class_epc": [ "Vitamin C [EPC]", "Non-Standardized Food Allergenic Extract [EPC]" ], "pharm_class_cs": [ "Ascorbic Acid [CS]", "Allergens [CS]", "Dietary Proteins [CS]" ], "pharm_class_pe": [ "Increased Histamine Release [PE]", "Cell-mediated Immunity [PE]" ], "unii": [ "PQ6CK8PD0R", "Q28R5GF371", "G72JA9DHK5", "VB06AV5US8", "3C18L6RJAZ", "DL6OZ476V3", "LZB7TFX1LT", "Z4B6561488", "S72O3284MS", "R5I1HK0UBL", "3B8D35Y7S4", "24K790T39B", "70FD1KFU70", "L11K75P92J", "91GQH8I5F7", "S6G2NLH4Y7", "W8N8R55022", "85I1Z426OV", "VP2CN2G7Y8", "190Q9MB3U3", "883WKN7W8X", "5HOC10FSIC", "324Y4038G2", "0B4FDL9I6P", "6P669D8HQ8", "5UAU16Z1U4", "12SEC09GR1", "29SUH5R3HU" ] } } ] }