{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-06-03",
    "results": {
      "skip": 0,
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      "total": 157
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  },
  "results": [
    {
      "spl_product_data_elements": [
        "nasal decongestant Oxymetazoline hydrochloride OXYMETAZOLINE HYDROCHLORIDE OXYMETAZOLINE BENZALKONIUM CHLORIDE BENZYL ALCOHOL SODIUM PHOSPHATE, DIBASIC, UNSPECIFIED FORM EDETATE DISODIUM EUCALYPTOL MENTHOL, UNSPECIFIED FORM MICROCRYSTALLINE CELLULOSE CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED SODIUM PHOSPHATE, MONOBASIC, UNSPECIFIED FORM POLYETHYLENE GLYCOL, UNSPECIFIED POVIDONE, UNSPECIFIED PROPYLENE GLYCOL WATER off white"
      ],
      "active_ingredient": [
        "Active ingredient Oxymetazoline hydrochloride 0.05%"
      ],
      "purpose": [
        "Purpose Nasal decongestant"
      ],
      "indications_and_usage": [
        "Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies • temporarily relieves sinus congestion and pressure • shrinks swollen nasal membranes so you can breathe more freely"
      ],
      "warnings": [
        "Warnings Ask a doctor before use if you have • heart disease • high blood pressure • thyroid disease • diabetes • trouble urinating due to an enlarged prostate gland When using this product • do not use more than directed • do not use for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen. • temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge may occur • use of this container by more than one person may spread infection Stop use and ask a doctor if symptoms persist If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away (1-800-222-1222)."
      ],
      "ask_doctor": [
        "Ask a doctor before use if you have • heart disease • high blood pressure • thyroid disease • diabetes • trouble urinating due to an enlarged prostate gland"
      ],
      "when_using": [
        "When using this product • do not use more than directed • do not use for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen. • temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge may occur • use of this container by more than one person may spread infection"
      ],
      "stop_use": [
        "Stop use and ask a doctor if symptoms persist"
      ],
      "pregnancy_or_breast_feeding": [
        "If pregnant or breast-feeding, ask a health professional before use."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away (1-800-222-1222)."
      ],
      "dosage_and_administration": [
        "Directions • adults and children 6 to under 12 years of age (with adult supervision): 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. Do not exceed 2 doses in any 24-hour period. • children under 6 years of age: ask a doctor To Use: Shake well before use. Hold white tabs, SQUEEZE grooved area of cap FIRMLY and turn counter clockwise. Before using the first time, prime metered pump by depressing pump firmly several times. To spray, hold bottle with thumb at base and nozzle between first and second fingers. Without tilting head, insert nozzle into nostril. Fully depress rim with a firm, even stroke and sniff deeply. Wipe nozzle clean after use. Secure cap after use."
      ],
      "storage_and_handling": [
        "Other information • store at 20-25°C (68-77°F) • retain carton for future reference on full labeling"
      ],
      "inactive_ingredient": [
        "Inactive ingredients benzalkonium chloride solution, benzyl alcohol, camphor, dibasic sodium phosphate, edetate disodium, eucalyptol, menthol, microcrystalline cellulose and carboxymethylcellulose sodium, monobasic sodium phosphate, polyethylene glycol, povidone, propylene glycol, purified water"
      ],
      "questions": [
        "Questions or comments? 1-800-719-9260"
      ],
      "package_label_principal_display_panel": [
        "Package/Label Principal Display Panel COMPARE TO Afrin ® No Drip active ingredient Signature SELECT ® SEVERE CONGESTION NASAL DECONGESTANT OXYMETAZOLINE HCl 0.05% #1 Doctor Recommended Adult Nasal Spray Active Ingredient NO DRIP PUMP MIST LOVE IT OR IT’S ON US • Won’t Drip From Nose Or Down Throat • Fast, Powerful Congestion Relief • For Colds & Allergies • Maximum Strength plus Menthol 12 HOUR RELIEF 1 FL OZ (30 mL) nasal-decongestant"
      ],
      "set_id": "03332596-2c37-4771-b13b-ab766e616866",
      "id": "90c73a7b-dd3b-4624-948d-d6a5ccd57799",
      "effective_time": "20260310",
      "version": "2",
      "openfda": {
        "application_number": [
          "M012"
        ],
        "brand_name": [
          "nasal decongestant"
        ],
        "generic_name": [
          "OXYMETAZOLINE HYDROCHLORIDE"
        ],
        "manufacturer_name": [
          "Safeway"
        ],
        "product_ndc": [
          "21130-837"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "NASAL"
        ],
        "substance_name": [
          "OXYMETAZOLINE HYDROCHLORIDE"
        ],
        "rxcui": [
          "1000990"
        ],
        "spl_id": [
          "90c73a7b-dd3b-4624-948d-d6a5ccd57799"
        ],
        "spl_set_id": [
          "03332596-2c37-4771-b13b-ab766e616866"
        ],
        "package_ndc": [
          "21130-837-10"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "K89MJ0S5VY"
        ]
      }
    }
  ]
}