{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-05-12",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Caffeine Mix 1003 Caffeine Mix SUS SCROFA ADRENAL GLAND SUS SCROFA ADRENAL GLAND CORTICOTROPIN CORTICOTROPIN HISTAMINE DIHYDROCHLORIDE HISTAMINE BEEF LIVER BEEF LIVER CAFFEINE CAFFEINE COCOA COCOA COFFEE BEAN COFFEE BEAN HIGH FRUCTOSE CORN SYRUP HIGH FRUCTOSE CORN SYRUP TEA LEAF TEA LEAF ALCOHOL WATER"
      ],
      "active_ingredient": [
        "ACTIVE INGREDIENTS Adrenal 6X ACTH 6X, 30X Histaminum hydrochloricum 12X Liver 6X, 12X and all the following Methylxanthine-bearing foods at 6X, 12X, 60X, 100X: Caffeine Chocolate (dark/milk/white) Coffee Decaffeinated Coffee Cola Espresso Tea"
      ],
      "questions": [
        "QUESTIONS Professional Formulas PO Box 2034 Lake Oswego, OR 97035"
      ],
      "indications_and_usage": [
        "INDICATIONS For the temporary relief of headache, anxiousness, irritability, fatigue, and itching of the nose or throat due to sensitivity to caffeine.*"
      ],
      "purpose": [
        "*Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated."
      ],
      "warnings": [
        "WARNINGS In case of overdose, get medical help or contact a poison control center right away. Keep out of the reach of children. If pregnant or breastfeeding, ask a healthcare professional before use."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of the reach of children."
      ],
      "pregnancy_or_breast_feeding": [
        "If pregnant or breastfeeding, ask a healthcare professional before use."
      ],
      "dosage_and_administration": [
        "DIRECTIONS Place drops under tongue 30 minutes before/after meals. Adults and children 12 years and over: Take 10 to 15 drops up to 3 times per day. For desensitization, begin with 1 to 5 drops daily, increasing to the standard dose gradually to avoid symptom expression; after 1 to 3 months at the standard dose, decrease gradually to a maintenance dose of 10 to 15 drops weekly. Consult a physician for use in children under 12 years of age."
      ],
      "other_safety_information": [
        "OTHER INFORMATION Tamper resistant. If seal is broken, do not use. After opening, close container tightly and store at room temperature away from heat."
      ],
      "inactive_ingredient": [
        "INACTIVE INGREDIENTS 20% ethanol, purified water."
      ],
      "package_label_principal_display_panel": [
        "LABEL Est 1985 Professional Formulas Complementary Health Caffeine Mix Homeopathic Remedy 2 FL. OZ. (59 mL) Label image"
      ],
      "set_id": "ce7f9a40-6cb1-49d1-a36a-e0f292dd136e",
      "id": "15ca385a-2248-415d-8459-0bff76f3513b",
      "effective_time": "20260108",
      "version": "2",
      "openfda": {
        "brand_name": [
          "Caffeine Mix 1003"
        ],
        "generic_name": [
          "CAFFEINE MIX"
        ],
        "manufacturer_name": [
          "Professional Complementary Health Formulas"
        ],
        "product_ndc": [
          "63083-1003"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "ORAL"
        ],
        "substance_name": [
          "BEEF LIVER",
          "CAFFEINE",
          "COCOA",
          "COFFEE BEAN",
          "CORTICOTROPIN",
          "HIGH FRUCTOSE CORN SYRUP",
          "HISTAMINE DIHYDROCHLORIDE",
          "SUS SCROFA ADRENAL GLAND",
          "TEA LEAF"
        ],
        "spl_id": [
          "15ca385a-2248-415d-8459-0bff76f3513b"
        ],
        "spl_set_id": [
          "ce7f9a40-6cb1-49d1-a36a-e0f292dd136e"
        ],
        "package_ndc": [
          "63083-1003-2"
        ],
        "is_original_packager": [
          true
        ],
        "nui": [
          "N0000185371",
          "N0000175629",
          "N0000184306",
          "M0000728",
          "M0006342",
          "N0000185017",
          "N0000175739",
          "N0000175729",
          "N0000175790",
          "M0023046",
          "M0016962",
          "M0000499",
          "N0000175941",
          "N0000185375"
        ],
        "pharm_class_epc": [
          "Non-Standardized Food Allergenic Extract [EPC]",
          "Central Nervous System Stimulant [EPC]",
          "Methylxanthine [EPC]",
          "Adrenocorticotropic Hormone [EPC]",
          "Non-Standardized Plant Allergenic Extract [EPC]"
        ],
        "pharm_class_pe": [
          "Increased Histamine Release [PE]",
          "Cell-mediated Immunity [PE]",
          "Central Nervous System Stimulation [PE]"
        ],
        "pharm_class_cs": [
          "Allergens [CS]",
          "Dietary Proteins [CS]",
          "Xanthines [CS]",
          "Plant Proteins [CS]",
          "Adrenocorticotropic Hormone [CS]"
        ],
        "unii": [
          "W8N8R55022",
          "3G6A5W338E",
          "D9108TZ9KG",
          "JFH385Y744",
          "K0U68Q2TXA",
          "XY6UN3QB6S",
          "3POA0Q644U",
          "398IYQ16YV",
          "GH42T47V24"
        ]
      }
    }
  ]
}