{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-14",
    "results": {
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  "results": [
    {
      "spl_product_data_elements": [
        "Differin 10% BPO Acne Treatment benzoyl peroxide Benzoyl Peroxide Benzoyl Peroxide Butyl Acrylate/Methyl Methacrylate/Methacrylic Acid Copolymer (18000 Mw) Carbomer Homopolymer, Unspecified Type Docusate Sodium Edetate Disodium Anhydrous Glycerin Poloxamer 182 Propylene Glycol Silicon Dioxide Sodium Hydroxide Water P57672-0 carton image"
      ],
      "active_ingredient": [
        "Active Ingredients Benzoyl Peroxide 10%"
      ],
      "purpose": [
        "Purpose Acne treatment"
      ],
      "indications_and_usage": [
        "Uses For the treatment of acne"
      ],
      "warnings": [
        "Warnings For external use only. Do not use if you ■ have very sensitive skin ■ are sensitive to benzoyl peroxide When using this product ■ skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. ■ avoid unnecessary sun exposure and use a sunscreen ■ avoid contact with the eyes, lips, and mouth ■ avoid contact with hair and dyed fabrics, which may be bleached by this product ■ skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. Stop use and ask a doctor if ■ irritation becomes severe."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions • Sensitivity Test for a New User . Apply product sparingly to one or two small affected areas during the first 3 days. If no discomfort occurs, follow the directions stated below ■ clean the skin thoroughly before applying this product ■ cover the entire affected area with a thin layer one to three times daily ■ because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor ■ if bothersome dryness or peeling occurs, reduce application to once a day or every other day ■ if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor"
      ],
      "inactive_ingredient": [
        "Inactive Ingredients Acrylates Copolymer, Carbomer, Diethylhexyl Sodium Sulfosuccinate, Disodium EDTA, Glycerin, Poloxamer 182, Propylene Glycol, Silica, Sodium Hydroxide, Water"
      ],
      "storage_and_handling": [
        ""
      ],
      "questions": [
        "Questions or comments? 1-866-735-4137",
        "Distributed by: Galderma Laboratories, L.P. Dallas, TX 75201 USA All trademarks are the property of their respective owners Made in Canada www.differin.com"
      ],
      "package_label_principal_display_panel": [
        "Principle Display Panel - 1 OZ (28 g) carton NEW DIFFERIN ® Acne Spot Treatment 10% BENZOYL PEROXIDE Acne Treatment MAXIMUM STRENGTH Reduces Acne Size & Redness VISIBLE RESULTS AFTER 1 DAY NET WT 1 OZ (28 g) P57672-0"
      ],
      "set_id": "05468eab-f239-42cb-9106-055a105f0fa5",
      "id": "d3de3a49-dad3-45dd-864d-632c7e7d3de9",
      "effective_time": "20240606",
      "version": "1",
      "openfda": {
        "application_number": [
          "M006"
        ],
        "brand_name": [
          "Differin 10% BPO Acne Treatment"
        ],
        "generic_name": [
          "BENZOYL PEROXIDE"
        ],
        "manufacturer_name": [
          "Galderma Laboratories, L.P."
        ],
        "product_ndc": [
          "0299-4611"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "TOPICAL"
        ],
        "substance_name": [
          "BENZOYL PEROXIDE"
        ],
        "spl_id": [
          "d3de3a49-dad3-45dd-864d-632c7e7d3de9"
        ],
        "spl_set_id": [
          "05468eab-f239-42cb-9106-055a105f0fa5"
        ],
        "package_ndc": [
          "0299-4611-00"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "W9WZN9A0GM"
        ]
      }
    }
  ]
}