{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "FATIGUE",
      "count": 6734
    },
    {
      "term": "NAUSEA",
      "count": 4945
    },
    {
      "term": "NEUTROPENIA",
      "count": 4670
    },
    {
      "term": "DIARRHOEA",
      "count": 4058
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 4008
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 3657
    },
    {
      "term": "ALOPECIA",
      "count": 3468
    },
    {
      "term": "ARTHRALGIA",
      "count": 3461
    },
    {
      "term": "PAIN",
      "count": 2836
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 2663
    },
    {
      "term": "ASTHENIA",
      "count": 2605
    },
    {
      "term": "DYSPNOEA",
      "count": 2541
    },
    {
      "term": "DEATH",
      "count": 2519
    },
    {
      "term": "VOMITING",
      "count": 2454
    },
    {
      "term": "HEADACHE",
      "count": 2118
    },
    {
      "term": "ANAEMIA",
      "count": 2109
    },
    {
      "term": "METASTASES TO BONE",
      "count": 2105
    },
    {
      "term": "DECREASED APPETITE",
      "count": 2050
    },
    {
      "term": "DIZZINESS",
      "count": 1923
    },
    {
      "term": "MALAISE",
      "count": 1913
    },
    {
      "term": "OFF LABEL USE",
      "count": 1868
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 1843
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 1776
    },
    {
      "term": "PYREXIA",
      "count": 1733
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 1700
    },
    {
      "term": "COUGH",
      "count": 1696
    },
    {
      "term": "BACK PAIN",
      "count": 1674
    },
    {
      "term": "BREAST CANCER",
      "count": 1670
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1583
    },
    {
      "term": "CONSTIPATION",
      "count": 1575
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1533
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 1487
    },
    {
      "term": "HOT FLUSH",
      "count": 1468
    },
    {
      "term": "RASH",
      "count": 1457
    },
    {
      "term": "BONE PAIN",
      "count": 1420
    },
    {
      "term": "LEUKOPENIA",
      "count": 1376
    },
    {
      "term": "PRURITUS",
      "count": 1347
    },
    {
      "term": "FALL",
      "count": 1204
    },
    {
      "term": "PNEUMONIA",
      "count": 1198
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 1168
    },
    {
      "term": "INSOMNIA",
      "count": 1162
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 1158
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 1152
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 1144
    },
    {
      "term": "ANXIETY",
      "count": 1143
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 1109
    },
    {
      "term": "MYALGIA",
      "count": 1071
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 1032
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1024
    },
    {
      "term": "DEPRESSION",
      "count": 1007
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 1005
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 972
    },
    {
      "term": "STOMATITIS",
      "count": 929
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 925
    },
    {
      "term": "HYPERTENSION",
      "count": 899
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 890
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 886
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 854
    },
    {
      "term": "DRY SKIN",
      "count": 830
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 818
    },
    {
      "term": "COVID-19",
      "count": 807
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 785
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 778
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 759
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 757
    },
    {
      "term": "RED BLOOD CELL COUNT DECREASED",
      "count": 755
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 753
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 738
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 726
    },
    {
      "term": "PARAESTHESIA",
      "count": 717
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 712
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 697
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 687
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 685
    },
    {
      "term": "CHEST PAIN",
      "count": 683
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 677
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 677
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 668
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 667
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 634
    },
    {
      "term": "DYSPEPSIA",
      "count": 603
    },
    {
      "term": "ERYTHEMA",
      "count": 600
    },
    {
      "term": "DEHYDRATION",
      "count": 596
    },
    {
      "term": "EPISTAXIS",
      "count": 587
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 586
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 576
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 564
    },
    {
      "term": "ILLNESS",
      "count": 540
    },
    {
      "term": "INFECTION",
      "count": 540
    },
    {
      "term": "TUMOUR MARKER INCREASED",
      "count": 538
    },
    {
      "term": "SOMNOLENCE",
      "count": 534
    },
    {
      "term": "DECREASED IMMUNE RESPONSIVENESS",
      "count": 533
    },
    {
      "term": "FULL BLOOD COUNT DECREASED",
      "count": 512
    },
    {
      "term": "CHILLS",
      "count": 503
    },
    {
      "term": "DYSPHAGIA",
      "count": 502
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 498
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 491
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 485
    },
    {
      "term": "ASCITES",
      "count": 478
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 475
    }
  ]
}