{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 263
    },
    {
      "term": "HEADACHE",
      "count": 252
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 209
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 206
    },
    {
      "term": "ANGIOEDEMA",
      "count": 204
    },
    {
      "term": "DYSPHONIA",
      "count": 198
    },
    {
      "term": "SWELLING FACE",
      "count": 194
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 193
    },
    {
      "term": "SWOLLEN TONGUE",
      "count": 192
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 177
    },
    {
      "term": "HEREDITARY ANGIOEDEMA",
      "count": 140
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 104
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 85
    },
    {
      "term": "FATIGUE",
      "count": 70
    },
    {
      "term": "PAIN",
      "count": 56
    },
    {
      "term": "ASTHENIA",
      "count": 53
    },
    {
      "term": "NAUSEA",
      "count": 50
    },
    {
      "term": "VOMITING",
      "count": 50
    },
    {
      "term": "DIARRHOEA",
      "count": 48
    },
    {
      "term": "ANAEMIA",
      "count": 45
    },
    {
      "term": "DIZZINESS",
      "count": 45
    },
    {
      "term": "FALL",
      "count": 45
    },
    {
      "term": "MALAISE",
      "count": 44
    },
    {
      "term": "DEATH",
      "count": 40
    },
    {
      "term": "DYSPNOEA",
      "count": 40
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 40
    },
    {
      "term": "CONTUSION",
      "count": 38
    },
    {
      "term": "PNEUMONIA",
      "count": 38
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 38
    },
    {
      "term": "BACK PAIN",
      "count": 36
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 36
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 35
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 34
    },
    {
      "term": "RASH",
      "count": 34
    },
    {
      "term": "ARTHRALGIA",
      "count": 32
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 32
    },
    {
      "term": "COUGH",
      "count": 30
    },
    {
      "term": "INFLUENZA",
      "count": 30
    },
    {
      "term": "PRURITUS",
      "count": 29
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 28
    },
    {
      "term": "PYREXIA",
      "count": 28
    },
    {
      "term": "DRUG INTERACTION",
      "count": 27
    },
    {
      "term": "HAEMORRHAGE",
      "count": 26
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 26
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 25
    },
    {
      "term": "STRESS",
      "count": 24
    },
    {
      "term": "THERAPEUTIC RESPONSE DECREASED",
      "count": 23
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 22
    },
    {
      "term": "CHEST PAIN",
      "count": 22
    },
    {
      "term": "CONSTIPATION",
      "count": 22
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 21
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 21
    },
    {
      "term": "INSOMNIA",
      "count": 20
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 20
    },
    {
      "term": "DEPRESSION",
      "count": 19
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 19
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 19
    },
    {
      "term": "SOMNOLENCE",
      "count": 19
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 18
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 18
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 18
    },
    {
      "term": "ANXIETY",
      "count": 17
    },
    {
      "term": "COVID-19",
      "count": 17
    },
    {
      "term": "DEPRESSED MOOD",
      "count": 17
    },
    {
      "term": "HYPERTENSION",
      "count": 17
    },
    {
      "term": "JOINT SWELLING",
      "count": 17
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 17
    },
    {
      "term": "RENAL FAILURE",
      "count": 17
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 17
    },
    {
      "term": "ILLNESS",
      "count": 16
    },
    {
      "term": "SYNCOPE",
      "count": 16
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 16
    },
    {
      "term": "DECREASED APPETITE",
      "count": 15
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 15
    },
    {
      "term": "GINGIVAL BLEEDING",
      "count": 15
    },
    {
      "term": "HOSPITALISATION",
      "count": 15
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 15
    },
    {
      "term": "MYALGIA",
      "count": 15
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 15
    },
    {
      "term": "PANCREATITIS",
      "count": 15
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 14
    },
    {
      "term": "ALOPECIA",
      "count": 14
    },
    {
      "term": "BONE PAIN",
      "count": 14
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 14
    },
    {
      "term": "DEHYDRATION",
      "count": 14
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 14
    },
    {
      "term": "LIVER DISORDER",
      "count": 14
    },
    {
      "term": "OROPHARYNGEAL PAIN",
      "count": 14
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 14
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 14
    },
    {
      "term": "SEPSIS",
      "count": 14
    },
    {
      "term": "SWELLING",
      "count": 14
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 14
    },
    {
      "term": "BRONCHITIS",
      "count": 13
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 13
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 13
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 13
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 13
    },
    {
      "term": "INJURY",
      "count": 13
    },
    {
      "term": "PLATELET COUNT INCREASED",
      "count": 13
    }
  ]
}