{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 2597
    },
    {
      "term": "FATIGUE",
      "count": 1967
    },
    {
      "term": "DIARRHOEA",
      "count": 1845
    },
    {
      "term": "NAUSEA",
      "count": 1803
    },
    {
      "term": "PYREXIA",
      "count": 1710
    },
    {
      "term": "OFF LABEL USE",
      "count": 1587
    },
    {
      "term": "PAIN",
      "count": 1501
    },
    {
      "term": "ARTHRALGIA",
      "count": 1458
    },
    {
      "term": "VOMITING",
      "count": 1438
    },
    {
      "term": "NEUTROPENIA",
      "count": 1405
    },
    {
      "term": "ASTHENIA",
      "count": 1363
    },
    {
      "term": "HEADACHE",
      "count": 1204
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 1170
    },
    {
      "term": "ANAEMIA",
      "count": 1125
    },
    {
      "term": "DYSPNOEA",
      "count": 1092
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1078
    },
    {
      "term": "MALAISE",
      "count": 988
    },
    {
      "term": "DEATH",
      "count": 983
    },
    {
      "term": "OSTEONECROSIS",
      "count": 978
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 967
    },
    {
      "term": "DIZZINESS",
      "count": 890
    },
    {
      "term": "METASTASES TO BONE",
      "count": 882
    },
    {
      "term": "PNEUMONIA",
      "count": 877
    },
    {
      "term": "BACK PAIN",
      "count": 846
    },
    {
      "term": "MYALGIA",
      "count": 827
    },
    {
      "term": "FALL",
      "count": 791
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 775
    },
    {
      "term": "BONE PAIN",
      "count": 721
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 714
    },
    {
      "term": "COUGH",
      "count": 711
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 664
    },
    {
      "term": "CHILLS",
      "count": 657
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 645
    },
    {
      "term": "CONSTIPATION",
      "count": 633
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 625
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 614
    },
    {
      "term": "RASH",
      "count": 613
    },
    {
      "term": "PRURITUS",
      "count": 597
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 559
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 531
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 528
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 523
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 500
    },
    {
      "term": "SEPSIS",
      "count": 489
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 481
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 480
    },
    {
      "term": "INSOMNIA",
      "count": 468
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 467
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 441
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 437
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 434
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 423
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 421
    },
    {
      "term": "INFLUENZA LIKE ILLNESS",
      "count": 412
    },
    {
      "term": "PAIN IN JAW",
      "count": 405
    },
    {
      "term": "SOMNOLENCE",
      "count": 403
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 398
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 392
    },
    {
      "term": "HYPERTENSION",
      "count": 390
    },
    {
      "term": "BONE DISORDER",
      "count": 389
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 389
    },
    {
      "term": "SYNCOPE",
      "count": 388
    },
    {
      "term": "TACHYCARDIA",
      "count": 387
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 380
    },
    {
      "term": "PLASMA CELL MYELOMA",
      "count": 348
    },
    {
      "term": "EYE PAIN",
      "count": 342
    },
    {
      "term": "INFECTION",
      "count": 340
    },
    {
      "term": "LEUKOPENIA",
      "count": 337
    },
    {
      "term": "ALOPECIA",
      "count": 336
    },
    {
      "term": "CHEST PAIN",
      "count": 331
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 323
    },
    {
      "term": "DEHYDRATION",
      "count": 322
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 320
    },
    {
      "term": "VISION BLURRED",
      "count": 319
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 317
    },
    {
      "term": "HYPOTENSION",
      "count": 316
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 307
    },
    {
      "term": "COVID-19",
      "count": 304
    },
    {
      "term": "DRUG INTERACTION",
      "count": 303
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 303
    },
    {
      "term": "PARAESTHESIA",
      "count": 299
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 294
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 293
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 288
    },
    {
      "term": "TINNITUS",
      "count": 283
    },
    {
      "term": "ASCITES",
      "count": 274
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 274
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 273
    },
    {
      "term": "FEMUR FRACTURE",
      "count": 269
    },
    {
      "term": "HAEMATURIA",
      "count": 268
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 267
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 264
    },
    {
      "term": "RENAL FAILURE",
      "count": 263
    },
    {
      "term": "ANXIETY",
      "count": 262
    },
    {
      "term": "HYPOPHOSPHATAEMIA",
      "count": 262
    },
    {
      "term": "BLINDNESS",
      "count": 258
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 256
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 256
    },
    {
      "term": "TOOTH EXTRACTION",
      "count": 255
    },
    {
      "term": "JOINT SWELLING",
      "count": 253
    }
  ]
}