{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 4387
    },
    {
      "term": "PYREXIA",
      "count": 1903
    },
    {
      "term": "NEUTROPENIA",
      "count": 1765
    },
    {
      "term": "OFF LABEL USE",
      "count": 1709
    },
    {
      "term": "SEPSIS",
      "count": 1105
    },
    {
      "term": "VOMITING",
      "count": 1038
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 1009
    },
    {
      "term": "NAUSEA",
      "count": 960
    },
    {
      "term": "PANCYTOPENIA",
      "count": 936
    },
    {
      "term": "PNEUMONIA",
      "count": 933
    },
    {
      "term": "HYPOTENSION",
      "count": 884
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 863
    },
    {
      "term": "DEATH",
      "count": 834
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 831
    },
    {
      "term": "ANAEMIA",
      "count": 827
    },
    {
      "term": "DIARRHOEA",
      "count": 770
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 768
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 739
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 717
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 706
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 688
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 675
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 670
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 661
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 660
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 649
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 597
    },
    {
      "term": "SECOND PRIMARY MALIGNANCY",
      "count": 568
    },
    {
      "term": "FATIGUE",
      "count": 550
    },
    {
      "term": "INFECTION",
      "count": 545
    },
    {
      "term": "TACHYCARDIA",
      "count": 539
    },
    {
      "term": "ASTHENIA",
      "count": 534
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 521
    },
    {
      "term": "DYSPNOEA",
      "count": 511
    },
    {
      "term": "HEADACHE",
      "count": 509
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 461
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 461
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 438
    },
    {
      "term": "CONSTIPATION",
      "count": 427
    },
    {
      "term": "LEUKOPENIA",
      "count": 402
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 382
    },
    {
      "term": "STOMATITIS",
      "count": 374
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 371
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 370
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 367
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 359
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 350
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 344
    },
    {
      "term": "COUGH",
      "count": 344
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA",
      "count": 341
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 338
    },
    {
      "term": "DECREASED APPETITE",
      "count": 336
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 332
    },
    {
      "term": "DEHYDRATION",
      "count": 329
    },
    {
      "term": "SEIZURE",
      "count": 329
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA RECURRENT",
      "count": 325
    },
    {
      "term": "COVID-19",
      "count": 302
    },
    {
      "term": "COLITIS",
      "count": 301
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 297
    },
    {
      "term": "CHILLS",
      "count": 293
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 280
    },
    {
      "term": "FEBRILE BONE MARROW APLASIA",
      "count": 278
    },
    {
      "term": "HYPERBILIRUBINAEMIA",
      "count": 278
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 273
    },
    {
      "term": "HYPERTENSION",
      "count": 272
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 270
    },
    {
      "term": "PAIN",
      "count": 270
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 270
    },
    {
      "term": "HYPOXIA",
      "count": 269
    },
    {
      "term": "DIZZINESS",
      "count": 267
    },
    {
      "term": "ASCITES",
      "count": 265
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 264
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 260
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 257
    },
    {
      "term": "RENAL FAILURE",
      "count": 257
    },
    {
      "term": "CARDIAC ARREST",
      "count": 255
    },
    {
      "term": "MALAISE",
      "count": 252
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 250
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 248
    },
    {
      "term": "BLOOD CULTURE POSITIVE",
      "count": 247
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 245
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 242
    },
    {
      "term": "PANCREATITIS",
      "count": 240
    },
    {
      "term": "VIRAL INFECTION",
      "count": 238
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 236
    },
    {
      "term": "BACK PAIN",
      "count": 233
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 233
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 229
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 227
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 220
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 219
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 215
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 213
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 213
    },
    {
      "term": "DRUG INTERACTION",
      "count": 211
    },
    {
      "term": "NEUROTOXICITY",
      "count": 209
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 208
    },
    {
      "term": "SECONDARY IMMUNODEFICIENCY",
      "count": 208
    },
    {
      "term": "ARTHRALGIA",
      "count": 207
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 207
    }
  ]
}