{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 2631
    },
    {
      "term": "NEUTROPENIA",
      "count": 2580
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 2332
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 1910
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 1703
    },
    {
      "term": "ANAEMIA",
      "count": 1411
    },
    {
      "term": "DEATH",
      "count": 1337
    },
    {
      "term": "PNEUMONIA",
      "count": 1313
    },
    {
      "term": "PYREXIA",
      "count": 1307
    },
    {
      "term": "INFECTION",
      "count": 1120
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 1115
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 986
    },
    {
      "term": "CYTOPENIA",
      "count": 913
    },
    {
      "term": "DIARRHOEA",
      "count": 876
    },
    {
      "term": "COVID-19",
      "count": 861
    },
    {
      "term": "SEPSIS",
      "count": 823
    },
    {
      "term": "PANCYTOPENIA",
      "count": 813
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 787
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 772
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 724
    },
    {
      "term": "NAUSEA",
      "count": 639
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 630
    },
    {
      "term": "FATIGUE",
      "count": 588
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 550
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 440
    },
    {
      "term": "ASTHENIA",
      "count": 432
    },
    {
      "term": "HAEMORRHAGE",
      "count": 432
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 422
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 412
    },
    {
      "term": "CHRONIC LYMPHOCYTIC LEUKAEMIA",
      "count": 412
    },
    {
      "term": "VOMITING",
      "count": 392
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 358
    },
    {
      "term": "DYSPNOEA",
      "count": 347
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 344
    },
    {
      "term": "RICHTER^S SYNDROME",
      "count": 306
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 302
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 291
    },
    {
      "term": "LEUKOPENIA",
      "count": 290
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 287
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 286
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 283
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA RECURRENT",
      "count": 274
    },
    {
      "term": "HYPOTENSION",
      "count": 267
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 250
    },
    {
      "term": "RENAL FAILURE",
      "count": 249
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 236
    },
    {
      "term": "BACTERAEMIA",
      "count": 225
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 225
    },
    {
      "term": "COUGH",
      "count": 223
    },
    {
      "term": "DRUG INTERACTION",
      "count": 223
    },
    {
      "term": "DECREASED APPETITE",
      "count": 221
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 219
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 213
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 213
    },
    {
      "term": "FALL",
      "count": 207
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 204
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 203
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 202
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 202
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 200
    },
    {
      "term": "CONSTIPATION",
      "count": 200
    },
    {
      "term": "RASH",
      "count": 199
    },
    {
      "term": "SYNCOPE",
      "count": 197
    },
    {
      "term": "DIZZINESS",
      "count": 195
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 194
    },
    {
      "term": "BACK PAIN",
      "count": 192
    },
    {
      "term": "PLASMA CELL MYELOMA",
      "count": 189
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 188
    },
    {
      "term": "MALAISE",
      "count": 185
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 184
    },
    {
      "term": "HYPERTENSION",
      "count": 182
    },
    {
      "term": "CHILLS",
      "count": 181
    },
    {
      "term": "COVID-19 PNEUMONIA",
      "count": 181
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 177
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 174
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 173
    },
    {
      "term": "HEADACHE",
      "count": 173
    },
    {
      "term": "CELLULITIS",
      "count": 162
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 160
    },
    {
      "term": "PAIN",
      "count": 159
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 159
    },
    {
      "term": "INFLUENZA",
      "count": 157
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 156
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 155
    },
    {
      "term": "ARTHRALGIA",
      "count": 154
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 149
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 145
    },
    {
      "term": "RESPIRATORY TRACT INFECTION",
      "count": 142
    },
    {
      "term": "PNEUMONIA FUNGAL",
      "count": 141
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 140
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA",
      "count": 140
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 139
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 137
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 135
    },
    {
      "term": "EPISTAXIS",
      "count": 134
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 133
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 133
    },
    {
      "term": "SPLENOMEGALY",
      "count": 133
    },
    {
      "term": "CARDIAC ARREST",
      "count": 132
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 131
    }
  ]
}