{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 877
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 530
    },
    {
      "term": "OFF LABEL USE",
      "count": 488
    },
    {
      "term": "PYREXIA",
      "count": 453
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 341
    },
    {
      "term": "RASH",
      "count": 322
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 307
    },
    {
      "term": "DIARRHOEA",
      "count": 290
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 275
    },
    {
      "term": "PNEUMONIA",
      "count": 274
    },
    {
      "term": "SEPSIS",
      "count": 266
    },
    {
      "term": "HYPOTENSION",
      "count": 227
    },
    {
      "term": "RENAL FAILURE",
      "count": 222
    },
    {
      "term": "DYSPNOEA",
      "count": 214
    },
    {
      "term": "PRURITUS",
      "count": 213
    },
    {
      "term": "NAUSEA",
      "count": 200
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 193
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 191
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE INFECTION",
      "count": 166
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 162
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 159
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 158
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 158
    },
    {
      "term": "ERYTHEMA",
      "count": 152
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 152
    },
    {
      "term": "ANAEMIA",
      "count": 150
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 148
    },
    {
      "term": "VOMITING",
      "count": 143
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 142
    },
    {
      "term": "DEATH",
      "count": 141
    },
    {
      "term": "NEUTROPENIA",
      "count": 140
    },
    {
      "term": "PANCYTOPENIA",
      "count": 138
    },
    {
      "term": "INFECTION",
      "count": 135
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 134
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 128
    },
    {
      "term": "PAIN",
      "count": 123
    },
    {
      "term": "EOSINOPHILIA",
      "count": 122
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 122
    },
    {
      "term": "URTICARIA",
      "count": 122
    },
    {
      "term": "FATIGUE",
      "count": 120
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 119
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 117
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 114
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 110
    },
    {
      "term": "HEADACHE",
      "count": 109
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 107
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 107
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 107
    },
    {
      "term": "DRUG INTERACTION",
      "count": 104
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 103
    },
    {
      "term": "LINEAR IGA DISEASE",
      "count": 103
    },
    {
      "term": "ASTHENIA",
      "count": 101
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 101
    },
    {
      "term": "CARDIAC ARREST",
      "count": 100
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 99
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 98
    },
    {
      "term": "TACHYCARDIA",
      "count": 98
    },
    {
      "term": "BACK PAIN",
      "count": 97
    },
    {
      "term": "MALAISE",
      "count": 97
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 95
    },
    {
      "term": "DISSEMINATED INTRAVASCULAR COAGULATION",
      "count": 94
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 94
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 94
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 91
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 91
    },
    {
      "term": "RENAL TUBULAR NECROSIS",
      "count": 90
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 89
    },
    {
      "term": "COUGH",
      "count": 88
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 81
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 79
    },
    {
      "term": "HYPERTENSION",
      "count": 79
    },
    {
      "term": "VANCOMYCIN INFUSION REACTION",
      "count": 78
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 77
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 76
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 76
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 75
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 74
    },
    {
      "term": "DRUG ERUPTION",
      "count": 73
    },
    {
      "term": "DECREASED APPETITE",
      "count": 71
    },
    {
      "term": "LEUKOPENIA",
      "count": 71
    },
    {
      "term": "RENAL DISORDER",
      "count": 71
    },
    {
      "term": "COVID-19",
      "count": 68
    },
    {
      "term": "LIVER DISORDER",
      "count": 68
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 67
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 66
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 66
    },
    {
      "term": "ANXIETY",
      "count": 65
    },
    {
      "term": "CHILLS",
      "count": 65
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 65
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 64
    },
    {
      "term": "STAPHYLOCOCCAL BACTERAEMIA",
      "count": 64
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 64
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 63
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 62
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 62
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 62
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 62
    },
    {
      "term": "RED MAN SYNDROME",
      "count": 62
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 62
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 61
    }
  ]
}