{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 7621
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 5448
    },
    {
      "term": "OFF LABEL USE",
      "count": 4689
    },
    {
      "term": "PYREXIA",
      "count": 4353
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 2924
    },
    {
      "term": "RENAL FAILURE",
      "count": 2674
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 2574
    },
    {
      "term": "RASH",
      "count": 2560
    },
    {
      "term": "DIARRHOEA",
      "count": 2543
    },
    {
      "term": "SEPSIS",
      "count": 2518
    },
    {
      "term": "PNEUMONIA",
      "count": 2332
    },
    {
      "term": "HYPOTENSION",
      "count": 2315
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 2251
    },
    {
      "term": "DYSPNOEA",
      "count": 1993
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 1940
    },
    {
      "term": "NAUSEA",
      "count": 1896
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 1889
    },
    {
      "term": "DEATH",
      "count": 1885
    },
    {
      "term": "PAIN",
      "count": 1686
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 1655
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 1648
    },
    {
      "term": "VOMITING",
      "count": 1587
    },
    {
      "term": "NEUTROPENIA",
      "count": 1581
    },
    {
      "term": "PRURITUS",
      "count": 1532
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE INFECTION",
      "count": 1529
    },
    {
      "term": "DRUG INTERACTION",
      "count": 1488
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 1464
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 1443
    },
    {
      "term": "ANAEMIA",
      "count": 1424
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 1358
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 1286
    },
    {
      "term": "PANCYTOPENIA",
      "count": 1252
    },
    {
      "term": "ERYTHEMA",
      "count": 1179
    },
    {
      "term": "ANXIETY",
      "count": 1171
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1125
    },
    {
      "term": "FATIGUE",
      "count": 1122
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 1104
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 1096
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1051
    },
    {
      "term": "EOSINOPHILIA",
      "count": 1045
    },
    {
      "term": "ASTHENIA",
      "count": 1042
    },
    {
      "term": "TACHYCARDIA",
      "count": 1022
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 1022
    },
    {
      "term": "RENAL TUBULAR NECROSIS",
      "count": 1010
    },
    {
      "term": "INFECTION",
      "count": 1004
    },
    {
      "term": "CARDIAC ARREST",
      "count": 963
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 955
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 913
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 911
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 907
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 906
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 903
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 882
    },
    {
      "term": "HEADACHE",
      "count": 875
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 866
    },
    {
      "term": "MALAISE",
      "count": 846
    },
    {
      "term": "URTICARIA",
      "count": 831
    },
    {
      "term": "LEUKOPENIA",
      "count": 828
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 808
    },
    {
      "term": "LINEAR IGA DISEASE",
      "count": 793
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 785
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 782
    },
    {
      "term": "COUGH",
      "count": 775
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 772
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 770
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 766
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 752
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 748
    },
    {
      "term": "INJURY",
      "count": 747
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 740
    },
    {
      "term": "CHILLS",
      "count": 739
    },
    {
      "term": "HYPOXIA",
      "count": 739
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 733
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 726
    },
    {
      "term": "HYPERTENSION",
      "count": 698
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 690
    },
    {
      "term": "RENAL INJURY",
      "count": 688
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 687
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 685
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 679
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 678
    },
    {
      "term": "CELLULITIS",
      "count": 654
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 654
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 653
    },
    {
      "term": "DIZZINESS",
      "count": 650
    },
    {
      "term": "UNEVALUABLE EVENT",
      "count": 647
    },
    {
      "term": "RED MAN SYNDROME",
      "count": 633
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 627
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 621
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 611
    },
    {
      "term": "DEHYDRATION",
      "count": 609
    },
    {
      "term": "ARTHRALGIA",
      "count": 597
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 594
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 591
    },
    {
      "term": "ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS",
      "count": 585
    },
    {
      "term": "BACK PAIN",
      "count": 584
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 583
    },
    {
      "term": "FALL",
      "count": 564
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 557
    },
    {
      "term": "DEPRESSION",
      "count": 556
    }
  ]
}