{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 2287
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 1517
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1389
    },
    {
      "term": "NEUTROPENIA",
      "count": 1018
    },
    {
      "term": "LEUKOPENIA",
      "count": 836
    },
    {
      "term": "PYREXIA",
      "count": 769
    },
    {
      "term": "DIARRHOEA",
      "count": 713
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 708
    },
    {
      "term": "CYTOMEGALOVIRUS VIRAEMIA",
      "count": 703
    },
    {
      "term": "PANCYTOPENIA",
      "count": 668
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 652
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 558
    },
    {
      "term": "TRANSPLANT REJECTION",
      "count": 557
    },
    {
      "term": "ANAEMIA",
      "count": 539
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 513
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 453
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 453
    },
    {
      "term": "PNEUMONIA",
      "count": 438
    },
    {
      "term": "SEPSIS",
      "count": 428
    },
    {
      "term": "DRUG INTERACTION",
      "count": 403
    },
    {
      "term": "DEATH",
      "count": 358
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 351
    },
    {
      "term": "NAUSEA",
      "count": 347
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 342
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 319
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 311
    },
    {
      "term": "VOMITING",
      "count": 302
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 298
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 296
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 290
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 274
    },
    {
      "term": "BK VIRUS INFECTION",
      "count": 272
    },
    {
      "term": "RENAL FAILURE",
      "count": 272
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 260
    },
    {
      "term": "COVID-19",
      "count": 260
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 256
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 255
    },
    {
      "term": "CYTOMEGALOVIRUS COLITIS",
      "count": 254
    },
    {
      "term": "DYSPNOEA",
      "count": 253
    },
    {
      "term": "KIDNEY TRANSPLANT REJECTION",
      "count": 245
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 244
    },
    {
      "term": "INFECTION",
      "count": 243
    },
    {
      "term": "CYTOMEGALOVIRUS CHORIORETINITIS",
      "count": 238
    },
    {
      "term": "HYPOTENSION",
      "count": 238
    },
    {
      "term": "EPSTEIN-BARR VIRUS INFECTION",
      "count": 234
    },
    {
      "term": "FATIGUE",
      "count": 224
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 223
    },
    {
      "term": "POLYOMAVIRUS-ASSOCIATED NEPHROPATHY",
      "count": 215
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 211
    },
    {
      "term": "COUGH",
      "count": 211
    },
    {
      "term": "ASTHENIA",
      "count": 210
    },
    {
      "term": "THROMBOTIC MICROANGIOPATHY",
      "count": 210
    },
    {
      "term": "HYPERTENSION",
      "count": 208
    },
    {
      "term": "HEADACHE",
      "count": 206
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 206
    },
    {
      "term": "POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER",
      "count": 203
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 196
    },
    {
      "term": "LYMPHOPENIA",
      "count": 196
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 191
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 189
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 187
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 186
    },
    {
      "term": "DECREASED APPETITE",
      "count": 181
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 181
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 179
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 177
    },
    {
      "term": "NOCARDIOSIS",
      "count": 171
    },
    {
      "term": "KLEBSIELLA INFECTION",
      "count": 165
    },
    {
      "term": "TREMOR",
      "count": 165
    },
    {
      "term": "ESCHERICHIA INFECTION",
      "count": 163
    },
    {
      "term": "RASH",
      "count": 156
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 155
    },
    {
      "term": "PSEUDOMONAS INFECTION",
      "count": 154
    },
    {
      "term": "COLITIS",
      "count": 152
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 152
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 152
    },
    {
      "term": "IMMUNOSUPPRESSANT DRUG LEVEL INCREASED",
      "count": 151
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 150
    },
    {
      "term": "ENCEPHALITIS CYTOMEGALOVIRUS",
      "count": 149
    },
    {
      "term": "RENAL TUBULAR NECROSIS",
      "count": 146
    },
    {
      "term": "COMPLICATIONS OF TRANSPLANTED KIDNEY",
      "count": 144
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 143
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 141
    },
    {
      "term": "MUCORMYCOSIS",
      "count": 140
    },
    {
      "term": "CYTOPENIA",
      "count": 139
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 138
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 138
    },
    {
      "term": "MALAISE",
      "count": 136
    },
    {
      "term": "PNEUMONIA CYTOMEGALOVIRAL",
      "count": 135
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 132
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 131
    },
    {
      "term": "CYSTITIS HAEMORRHAGIC",
      "count": 130
    },
    {
      "term": "HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS",
      "count": 129
    },
    {
      "term": "TRANSPLANT DYSFUNCTION",
      "count": 129
    },
    {
      "term": "PAIN",
      "count": 127
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 127
    },
    {
      "term": "DIZZINESS",
      "count": 126
    },
    {
      "term": "DELAYED GRAFT FUNCTION",
      "count": 124
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 123
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 123
    }
  ]
}