{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 1207
    },
    {
      "term": "PYREXIA",
      "count": 806
    },
    {
      "term": "NEUTROPENIA",
      "count": 740
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 733
    },
    {
      "term": "DIARRHOEA",
      "count": 731
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 686
    },
    {
      "term": "FATIGUE",
      "count": 664
    },
    {
      "term": "NAUSEA",
      "count": 657
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 578
    },
    {
      "term": "PNEUMONIA",
      "count": 546
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 530
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 507
    },
    {
      "term": "COVID-19",
      "count": 499
    },
    {
      "term": "HEADACHE",
      "count": 481
    },
    {
      "term": "ASTHENIA",
      "count": 449
    },
    {
      "term": "ANAEMIA",
      "count": 426
    },
    {
      "term": "PAIN",
      "count": 407
    },
    {
      "term": "VOMITING",
      "count": 398
    },
    {
      "term": "RASH",
      "count": 396
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 393
    },
    {
      "term": "DYSPNOEA",
      "count": 391
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 357
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 354
    },
    {
      "term": "COUGH",
      "count": 326
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 323
    },
    {
      "term": "ARTHRALGIA",
      "count": 313
    },
    {
      "term": "DIZZINESS",
      "count": 302
    },
    {
      "term": "CONSTIPATION",
      "count": 296
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 278
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 277
    },
    {
      "term": "DEATH",
      "count": 277
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 271
    },
    {
      "term": "HYPOTENSION",
      "count": 258
    },
    {
      "term": "MALAISE",
      "count": 258
    },
    {
      "term": "PANCYTOPENIA",
      "count": 244
    },
    {
      "term": "DECREASED APPETITE",
      "count": 240
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 236
    },
    {
      "term": "ANXIETY",
      "count": 233
    },
    {
      "term": "HERPES ZOSTER",
      "count": 224
    },
    {
      "term": "PRURITUS",
      "count": 222
    },
    {
      "term": "INFECTION",
      "count": 218
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 216
    },
    {
      "term": "FALL",
      "count": 213
    },
    {
      "term": "SEPSIS",
      "count": 213
    },
    {
      "term": "BACK PAIN",
      "count": 212
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 209
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 205
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 201
    },
    {
      "term": "CHOLESTASIS",
      "count": 198
    },
    {
      "term": "INSOMNIA",
      "count": 194
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 194
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 193
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 189
    },
    {
      "term": "RENAL FAILURE",
      "count": 187
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 179
    },
    {
      "term": "HYPERTENSION",
      "count": 174
    },
    {
      "term": "NEUROTOXICITY",
      "count": 174
    },
    {
      "term": "ERYTHEMA",
      "count": 172
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 169
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 169
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 168
    },
    {
      "term": "LEUKOPENIA",
      "count": 166
    },
    {
      "term": "DRUG INTERACTION",
      "count": 158
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 158
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 154
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 150
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 150
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 149
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 148
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 147
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 146
    },
    {
      "term": "DEPRESSION",
      "count": 144
    },
    {
      "term": "MYALGIA",
      "count": 143
    },
    {
      "term": "FEBRILE BONE MARROW APLASIA",
      "count": 138
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 137
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 137
    },
    {
      "term": "LUNG DISORDER",
      "count": 136
    },
    {
      "term": "SOMNOLENCE",
      "count": 135
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 134
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 132
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA",
      "count": 130
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 130
    },
    {
      "term": "CHILLS",
      "count": 129
    },
    {
      "term": "PLASMA CELL MYELOMA",
      "count": 128
    },
    {
      "term": "BRONCHITIS",
      "count": 126
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 126
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 125
    },
    {
      "term": "COVID-19 PNEUMONIA",
      "count": 124
    },
    {
      "term": "IMMUNE EFFECTOR CELL-ASSOCIATED NEUROTOXICITY SYNDROME",
      "count": 122
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 121
    },
    {
      "term": "INFLUENZA",
      "count": 121
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 120
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 120
    },
    {
      "term": "ILLNESS",
      "count": 120
    },
    {
      "term": "SINUSITIS",
      "count": 120
    },
    {
      "term": "ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS",
      "count": 118
    },
    {
      "term": "EOSINOPHILIA",
      "count": 118
    },
    {
      "term": "ORAL HERPES",
      "count": 118
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 117
    },
    {
      "term": "PARAESTHESIA",
      "count": 117
    }
  ]
}