{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 2490
    },
    {
      "term": "OFF LABEL USE",
      "count": 2242
    },
    {
      "term": "FATIGUE",
      "count": 1382
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 1362
    },
    {
      "term": "ARTHRALGIA",
      "count": 1349
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 1323
    },
    {
      "term": "PAIN",
      "count": 1316
    },
    {
      "term": "RASH",
      "count": 1303
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 1302
    },
    {
      "term": "SYNOVITIS",
      "count": 1301
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 1273
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 1233
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 1232
    },
    {
      "term": "JOINT SWELLING",
      "count": 1200
    },
    {
      "term": "WOUND",
      "count": 1173
    },
    {
      "term": "HEADACHE",
      "count": 1172
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 1166
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 1159
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 1149
    },
    {
      "term": "ALOPECIA",
      "count": 1128
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 1127
    },
    {
      "term": "NAUSEA",
      "count": 1085
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 1081
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 1078
    },
    {
      "term": "ARTHROPATHY",
      "count": 1077
    },
    {
      "term": "GLOSSODYNIA",
      "count": 1063
    },
    {
      "term": "PEMPHIGUS",
      "count": 1062
    },
    {
      "term": "HAND DEFORMITY",
      "count": 1057
    },
    {
      "term": "CROHN^S DISEASE",
      "count": 1053
    },
    {
      "term": "PERICARDITIS",
      "count": 1053
    },
    {
      "term": "HYPERTENSION",
      "count": 1015
    },
    {
      "term": "DIARRHOEA",
      "count": 983
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 976
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 972
    },
    {
      "term": "SWELLING",
      "count": 962
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 952
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 952
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 944
    },
    {
      "term": "MALAISE",
      "count": 943
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 938
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 934
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 914
    },
    {
      "term": "DECREASED APPETITE",
      "count": 898
    },
    {
      "term": "PNEUMONIA",
      "count": 875
    },
    {
      "term": "DISCOMFORT",
      "count": 864
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 862
    },
    {
      "term": "INFECTION",
      "count": 852
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 849
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 831
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 829
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 821
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 808
    },
    {
      "term": "VOMITING",
      "count": 807
    },
    {
      "term": "BLISTER",
      "count": 799
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 773
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 772
    },
    {
      "term": "FIBROMYALGIA",
      "count": 757
    },
    {
      "term": "DYSPNOEA",
      "count": 756
    },
    {
      "term": "INJURY",
      "count": 753
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 752
    },
    {
      "term": "DIZZINESS",
      "count": 748
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 747
    },
    {
      "term": "FOLLICULITIS",
      "count": 742
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 741
    },
    {
      "term": "URTICARIA",
      "count": 724
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 707
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 698
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 696
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 691
    },
    {
      "term": "PYREXIA",
      "count": 685
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 683
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 656
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 639
    },
    {
      "term": "LIVER INJURY",
      "count": 636
    },
    {
      "term": "WHEEZING",
      "count": 631
    },
    {
      "term": "SINUSITIS",
      "count": 628
    },
    {
      "term": "STOMATITIS",
      "count": 627
    },
    {
      "term": "SLEEP DISORDER",
      "count": 620
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 610
    },
    {
      "term": "PRURITUS",
      "count": 590
    },
    {
      "term": "PSORIASIS",
      "count": 588
    },
    {
      "term": "INSOMNIA",
      "count": 573
    },
    {
      "term": "DYSPEPSIA",
      "count": 571
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 569
    },
    {
      "term": "INFLAMMATION",
      "count": 568
    },
    {
      "term": "MUSCLE INJURY",
      "count": 566
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 565
    },
    {
      "term": "SWOLLEN JOINT COUNT INCREASED",
      "count": 563
    },
    {
      "term": "HYPERCHOLESTEROLAEMIA",
      "count": 550
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 544
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 540
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 536
    },
    {
      "term": "WOUND INFECTION",
      "count": 536
    },
    {
      "term": "ADVERSE EVENT",
      "count": 526
    },
    {
      "term": "ADVERSE DRUG REACTION",
      "count": 525
    },
    {
      "term": "GAIT INABILITY",
      "count": 513
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 509
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 507
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 504
    },
    {
      "term": "CONTUSION",
      "count": 496
    }
  ]
}