{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 873
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 745
    },
    {
      "term": "PAIN",
      "count": 463
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 458
    },
    {
      "term": "VOMITING",
      "count": 431
    },
    {
      "term": "PARAESTHESIA",
      "count": 354
    },
    {
      "term": "RASH",
      "count": 350
    },
    {
      "term": "NAUSEA",
      "count": 348
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 347
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 334
    },
    {
      "term": "HEADACHE",
      "count": 326
    },
    {
      "term": "DIARRHOEA",
      "count": 325
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 314
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 311
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 304
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 304
    },
    {
      "term": "TASTE DISORDER",
      "count": 303
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 294
    },
    {
      "term": "EPILEPSY",
      "count": 289
    },
    {
      "term": "BLEPHAROSPASM",
      "count": 277
    },
    {
      "term": "ARTHRALGIA",
      "count": 265
    },
    {
      "term": "FATIGUE",
      "count": 257
    },
    {
      "term": "MIGRAINE",
      "count": 257
    },
    {
      "term": "PNEUMONIA",
      "count": 254
    },
    {
      "term": "DEPRESSION",
      "count": 250
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 248
    },
    {
      "term": "DIZZINESS",
      "count": 238
    },
    {
      "term": "ALOPECIA",
      "count": 227
    },
    {
      "term": "PRURITUS",
      "count": 222
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 222
    },
    {
      "term": "DIFFERENTIATION SYNDROME",
      "count": 218
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 217
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 214
    },
    {
      "term": "ASTHENIA",
      "count": 213
    },
    {
      "term": "PYREXIA",
      "count": 209
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 205
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 205
    },
    {
      "term": "URTICARIA",
      "count": 203
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 192
    },
    {
      "term": "DYSPNOEA",
      "count": 187
    },
    {
      "term": "HYPERTENSION",
      "count": 186
    },
    {
      "term": "ANXIETY",
      "count": 184
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 183
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 179
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 177
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 177
    },
    {
      "term": "DRY SKIN",
      "count": 176
    },
    {
      "term": "PERICARDITIS",
      "count": 176
    },
    {
      "term": "SLEEP DISORDER",
      "count": 176
    },
    {
      "term": "SWELLING",
      "count": 175
    },
    {
      "term": "SYNOVITIS",
      "count": 174
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 174
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 171
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 169
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 168
    },
    {
      "term": "DRY MOUTH",
      "count": 167
    },
    {
      "term": "WOUND",
      "count": 167
    },
    {
      "term": "BLISTER",
      "count": 166
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 166
    },
    {
      "term": "STOMATITIS",
      "count": 166
    },
    {
      "term": "NECK PAIN",
      "count": 162
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 162
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 161
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 160
    },
    {
      "term": "INFLAMMATION",
      "count": 159
    },
    {
      "term": "INJURY",
      "count": 159
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 159
    },
    {
      "term": "ARTHROPATHY",
      "count": 156
    },
    {
      "term": "NIGHT SWEATS",
      "count": 156
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 154
    },
    {
      "term": "ERYTHEMA",
      "count": 150
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 150
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 150
    },
    {
      "term": "JOINT SWELLING",
      "count": 148
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 147
    },
    {
      "term": "FOLLICULITIS",
      "count": 144
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 143
    },
    {
      "term": "PEMPHIGUS",
      "count": 143
    },
    {
      "term": "SKIN EXFOLIATION",
      "count": 143
    },
    {
      "term": "BREAST CANCER STAGE III",
      "count": 142
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 141
    },
    {
      "term": "GLOSSODYNIA",
      "count": 141
    },
    {
      "term": "BURSITIS",
      "count": 140
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 140
    },
    {
      "term": "INSOMNIA",
      "count": 140
    },
    {
      "term": "ONYCHOMADESIS",
      "count": 140
    },
    {
      "term": "PERIPHERAL VENOUS DISEASE",
      "count": 140
    },
    {
      "term": "BACK INJURY",
      "count": 138
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 137
    },
    {
      "term": "FIBROMYALGIA",
      "count": 137
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 137
    },
    {
      "term": "MUSCULOSKELETAL PAIN",
      "count": 136
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 136
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 134
    },
    {
      "term": "LIVE BIRTH",
      "count": 134
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 133
    },
    {
      "term": "LIP DRY",
      "count": 133
    },
    {
      "term": "NEUTROPENIA",
      "count": 132
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 129
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 129
    }
  ]
}