{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEPENDENCE",
      "count": 7841
    },
    {
      "term": "OVERDOSE",
      "count": 3998
    },
    {
      "term": "VOMITING",
      "count": 3624
    },
    {
      "term": "PAIN",
      "count": 3281
    },
    {
      "term": "NAUSEA",
      "count": 3272
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 3015
    },
    {
      "term": "OFF LABEL USE",
      "count": 2659
    },
    {
      "term": "HEADACHE",
      "count": 2651
    },
    {
      "term": "FATIGUE",
      "count": 2587
    },
    {
      "term": "DYSPNOEA",
      "count": 2569
    },
    {
      "term": "DIZZINESS",
      "count": 2284
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 2272
    },
    {
      "term": "ARTHRALGIA",
      "count": 2239
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 2222
    },
    {
      "term": "MALAISE",
      "count": 2176
    },
    {
      "term": "DIARRHOEA",
      "count": 2173
    },
    {
      "term": "PNEUMONIA",
      "count": 2115
    },
    {
      "term": "DEATH",
      "count": 1936
    },
    {
      "term": "DEPRESSION",
      "count": 1909
    },
    {
      "term": "WHEEZING",
      "count": 1886
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 1879
    },
    {
      "term": "HYPERTENSION",
      "count": 1871
    },
    {
      "term": "RASH",
      "count": 1800
    },
    {
      "term": "ASTHMA",
      "count": 1686
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 1684
    },
    {
      "term": "INSOMNIA",
      "count": 1666
    },
    {
      "term": "ASTHENIA",
      "count": 1658
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 1586
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 1562
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 1544
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 1525
    },
    {
      "term": "PYREXIA",
      "count": 1500
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 1495
    },
    {
      "term": "PRURITUS",
      "count": 1494
    },
    {
      "term": "FALL",
      "count": 1487
    },
    {
      "term": "JOINT SWELLING",
      "count": 1483
    },
    {
      "term": "DRUG INTERACTION",
      "count": 1457
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 1446
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 1436
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1435
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 1427
    },
    {
      "term": "FIBROMYALGIA",
      "count": 1415
    },
    {
      "term": "URTICARIA",
      "count": 1408
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 1394
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 1385
    },
    {
      "term": "SWELLING",
      "count": 1379
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 1374
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 1369
    },
    {
      "term": "ANXIETY",
      "count": 1362
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 1352
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 1343
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 1339
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 1328
    },
    {
      "term": "SYNOVITIS",
      "count": 1326
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 1318
    },
    {
      "term": "SLEEP DISORDER",
      "count": 1315
    },
    {
      "term": "OEDEMA",
      "count": 1310
    },
    {
      "term": "WOUND",
      "count": 1304
    },
    {
      "term": "INJURY",
      "count": 1293
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 1271
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 1258
    },
    {
      "term": "DRY MOUTH",
      "count": 1231
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1224
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 1216
    },
    {
      "term": "FOLLICULITIS",
      "count": 1207
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 1207
    },
    {
      "term": "GLOSSODYNIA",
      "count": 1206
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 1198
    },
    {
      "term": "ALOPECIA",
      "count": 1184
    },
    {
      "term": "HAND DEFORMITY",
      "count": 1175
    },
    {
      "term": "STOMATITIS",
      "count": 1166
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 1158
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 1152
    },
    {
      "term": "SOMNOLENCE",
      "count": 1150
    },
    {
      "term": "ARTHROPATHY",
      "count": 1135
    },
    {
      "term": "DRUG ABUSE",
      "count": 1134
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 1126
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 1119
    },
    {
      "term": "INFLAMMATION",
      "count": 1110
    },
    {
      "term": "PERICARDITIS",
      "count": 1108
    },
    {
      "term": "PEMPHIGUS",
      "count": 1104
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 1103
    },
    {
      "term": "CHEST PAIN",
      "count": 1097
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 1091
    },
    {
      "term": "BACK PAIN",
      "count": 1089
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1069
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 1062
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 1041
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 1038
    },
    {
      "term": "PARAESTHESIA",
      "count": 1036
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1022
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 1015
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 1012
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 1009
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 1009
    },
    {
      "term": "BLISTER",
      "count": 1007
    },
    {
      "term": "GAIT INABILITY",
      "count": 990
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 968
    },
    {
      "term": "LIVER INJURY",
      "count": 963
    },
    {
      "term": "LIP DRY",
      "count": 962
    }
  ]
}