{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "NEUTROPENIA",
      "count": 154
    },
    {
      "term": "ANAEMIA",
      "count": 130
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 130
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 106
    },
    {
      "term": "NAUSEA",
      "count": 103
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 101
    },
    {
      "term": "VOMITING",
      "count": 91
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 82
    },
    {
      "term": "ASTHENIA",
      "count": 70
    },
    {
      "term": "OFF LABEL USE",
      "count": 70
    },
    {
      "term": "FATIGUE",
      "count": 65
    },
    {
      "term": "PANCYTOPENIA",
      "count": 59
    },
    {
      "term": "PYREXIA",
      "count": 59
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 54
    },
    {
      "term": "LEUKOPENIA",
      "count": 54
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 52
    },
    {
      "term": "DIARRHOEA",
      "count": 44
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 44
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 43
    },
    {
      "term": "DYSPNOEA",
      "count": 41
    },
    {
      "term": "PNEUMONIA",
      "count": 41
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 40
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 38
    },
    {
      "term": "SEPSIS",
      "count": 36
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 35
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 31
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 30
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 29
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 28
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 28
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 28
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 27
    },
    {
      "term": "CONSTIPATION",
      "count": 27
    },
    {
      "term": "DECREASED APPETITE",
      "count": 26
    },
    {
      "term": "GAMMA-GLUTAMYLTRANSFERASE INCREASED",
      "count": 26
    },
    {
      "term": "RENAL FAILURE",
      "count": 26
    },
    {
      "term": "DEATH",
      "count": 25
    },
    {
      "term": "ASCITES",
      "count": 23
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 23
    },
    {
      "term": "MYALGIA",
      "count": 22
    },
    {
      "term": "HYPOTENSION",
      "count": 21
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 21
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 21
    },
    {
      "term": "DEHYDRATION",
      "count": 20
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 20
    },
    {
      "term": "DEVICE RELATED INFECTION",
      "count": 19
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 19
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 18
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 17
    },
    {
      "term": "CARDIOTOXICITY",
      "count": 16
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 16
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 16
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 16
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 16
    },
    {
      "term": "DRUG INTERACTION",
      "count": 15
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 15
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 15
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 15
    },
    {
      "term": "LYMPHANGIOLEIOMYOMATOSIS",
      "count": 15
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 15
    },
    {
      "term": "ALOPECIA",
      "count": 14
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 14
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 14
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 14
    },
    {
      "term": "EJECTION FRACTION DECREASED",
      "count": 14
    },
    {
      "term": "INFECTION",
      "count": 14
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 14
    },
    {
      "term": "PNEUMONITIS",
      "count": 14
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 13
    },
    {
      "term": "HYPERTRANSAMINASAEMIA",
      "count": 13
    },
    {
      "term": "LEFT VENTRICULAR DYSFUNCTION",
      "count": 13
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 13
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 13
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 13
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 12
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 12
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 12
    },
    {
      "term": "NEUROTOXICITY",
      "count": 12
    },
    {
      "term": "PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME",
      "count": 12
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 12
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 12
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 12
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 11
    },
    {
      "term": "HEADACHE",
      "count": 11
    },
    {
      "term": "LIVER DISORDER",
      "count": 11
    },
    {
      "term": "MALAISE",
      "count": 11
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 11
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 11
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 11
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 10
    },
    {
      "term": "HAEMATOCRIT DECREASED",
      "count": 10
    },
    {
      "term": "INTESTINAL OBSTRUCTION",
      "count": 10
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 10
    },
    {
      "term": "STOMATITIS",
      "count": 10
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 10
    },
    {
      "term": "BLAST CELLS PRESENT",
      "count": 9
    },
    {
      "term": "CARDIAC ARREST",
      "count": 9
    },
    {
      "term": "LUNG DISORDER",
      "count": 9
    },
    {
      "term": "MEAN CELL HAEMOGLOBIN DECREASED",
      "count": 9
    },
    {
      "term": "NEUTROPHIL PERCENTAGE DECREASED",
      "count": 9
    }
  ]
}