{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 5124
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 3857
    },
    {
      "term": "OFF LABEL USE",
      "count": 3772
    },
    {
      "term": "PAIN",
      "count": 3530
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 3438
    },
    {
      "term": "FATIGUE",
      "count": 3350
    },
    {
      "term": "RASH",
      "count": 3300
    },
    {
      "term": "JOINT SWELLING",
      "count": 3186
    },
    {
      "term": "SYNOVITIS",
      "count": 3005
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 2942
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 2937
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 2937
    },
    {
      "term": "ALOPECIA",
      "count": 2936
    },
    {
      "term": "HAND DEFORMITY",
      "count": 2929
    },
    {
      "term": "GLOSSODYNIA",
      "count": 2899
    },
    {
      "term": "PEMPHIGUS",
      "count": 2860
    },
    {
      "term": "SWELLING",
      "count": 2831
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 2823
    },
    {
      "term": "WOUND",
      "count": 2818
    },
    {
      "term": "ARTHROPATHY",
      "count": 2788
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 2776
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 2745
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 2739
    },
    {
      "term": "ARTHRALGIA",
      "count": 2702
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 2674
    },
    {
      "term": "PERICARDITIS",
      "count": 2588
    },
    {
      "term": "DISCOMFORT",
      "count": 2518
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 2460
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 2282
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 2176
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 2149
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 2126
    },
    {
      "term": "HEADACHE",
      "count": 2063
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 2024
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 1992
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 1981
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 1945
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 1920
    },
    {
      "term": "HYPERTENSION",
      "count": 1915
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 1881
    },
    {
      "term": "BLISTER",
      "count": 1738
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 1719
    },
    {
      "term": "NAUSEA",
      "count": 1673
    },
    {
      "term": "VOMITING",
      "count": 1622
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 1606
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 1595
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 1591
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 1583
    },
    {
      "term": "DIARRHOEA",
      "count": 1547
    },
    {
      "term": "FIBROMYALGIA",
      "count": 1516
    },
    {
      "term": "INJURY",
      "count": 1494
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 1489
    },
    {
      "term": "INFECTION",
      "count": 1463
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1458
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 1449
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 1431
    },
    {
      "term": "FOLLICULITIS",
      "count": 1381
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 1377
    },
    {
      "term": "MALAISE",
      "count": 1371
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 1340
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 1338
    },
    {
      "term": "LIVER INJURY",
      "count": 1336
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 1335
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 1333
    },
    {
      "term": "PNEUMONIA",
      "count": 1321
    },
    {
      "term": "URTICARIA",
      "count": 1321
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1266
    },
    {
      "term": "WHEEZING",
      "count": 1258
    },
    {
      "term": "STOMATITIS",
      "count": 1253
    },
    {
      "term": "DYSPNOEA",
      "count": 1216
    },
    {
      "term": "MUSCLE INJURY",
      "count": 1209
    },
    {
      "term": "SWOLLEN JOINT COUNT INCREASED",
      "count": 1200
    },
    {
      "term": "PYREXIA",
      "count": 1196
    },
    {
      "term": "DIZZINESS",
      "count": 1171
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 1166
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 1132
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 1097
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 1065
    },
    {
      "term": "PRURITUS",
      "count": 1063
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 1050
    },
    {
      "term": "INFLAMMATION",
      "count": 1047
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 1040
    },
    {
      "term": "SINUSITIS",
      "count": 1031
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 1024
    },
    {
      "term": "MUSCULOSKELETAL PAIN",
      "count": 1012
    },
    {
      "term": "SLEEP DISORDER",
      "count": 1012
    },
    {
      "term": "ASTHENIA",
      "count": 988
    },
    {
      "term": "DEPRESSION",
      "count": 959
    },
    {
      "term": "DYSPEPSIA",
      "count": 953
    },
    {
      "term": "ADVERSE EVENT",
      "count": 950
    },
    {
      "term": "OEDEMA",
      "count": 932
    },
    {
      "term": "CONTUSION",
      "count": 914
    },
    {
      "term": "DRY MOUTH",
      "count": 908
    },
    {
      "term": "MIGRAINE",
      "count": 908
    },
    {
      "term": "WOUND INFECTION",
      "count": 908
    },
    {
      "term": "INSOMNIA",
      "count": 900
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 890
    },
    {
      "term": "BURSITIS",
      "count": 884
    },
    {
      "term": "PRESCRIBED OVERDOSE",
      "count": 884
    },
    {
      "term": "LUNG DISORDER",
      "count": 873
    }
  ]
}