{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 9091
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 6971
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 4889
    },
    {
      "term": "PAIN",
      "count": 4466
    },
    {
      "term": "FATIGUE",
      "count": 3874
    },
    {
      "term": "RASH",
      "count": 3783
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 3532
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 3283
    },
    {
      "term": "ARTHROPATHY",
      "count": 3278
    },
    {
      "term": "ALOPECIA",
      "count": 3204
    },
    {
      "term": "ARTHRALGIA",
      "count": 3184
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 3182
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 3141
    },
    {
      "term": "JOINT SWELLING",
      "count": 3098
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 3096
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 3089
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 3068
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 3064
    },
    {
      "term": "PEMPHIGUS",
      "count": 3060
    },
    {
      "term": "SYNOVITIS",
      "count": 3031
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 2956
    },
    {
      "term": "GLOSSODYNIA",
      "count": 2846
    },
    {
      "term": "WOUND",
      "count": 2726
    },
    {
      "term": "SWELLING",
      "count": 2717
    },
    {
      "term": "HEADACHE",
      "count": 2712
    },
    {
      "term": "HAND DEFORMITY",
      "count": 2703
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 2691
    },
    {
      "term": "NAUSEA",
      "count": 2424
    },
    {
      "term": "HYPERTENSION",
      "count": 2374
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 2310
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 2292
    },
    {
      "term": "PERICARDITIS",
      "count": 2269
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 2257
    },
    {
      "term": "PNEUMONIA",
      "count": 2230
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 2225
    },
    {
      "term": "DISCOMFORT",
      "count": 2205
    },
    {
      "term": "INFECTION",
      "count": 2190
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 2157
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 2149
    },
    {
      "term": "DIARRHOEA",
      "count": 2118
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 2091
    },
    {
      "term": "PYREXIA",
      "count": 2072
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 1991
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1981
    },
    {
      "term": "VOMITING",
      "count": 1912
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 1878
    },
    {
      "term": "MALAISE",
      "count": 1836
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 1712
    },
    {
      "term": "DIZZINESS",
      "count": 1695
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 1695
    },
    {
      "term": "LIVER INJURY",
      "count": 1684
    },
    {
      "term": "DYSPNOEA",
      "count": 1646
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 1623
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 1601
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 1601
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 1572
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 1571
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 1556
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1555
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 1529
    },
    {
      "term": "PRURITUS",
      "count": 1477
    },
    {
      "term": "URTICARIA",
      "count": 1464
    },
    {
      "term": "FIBROMYALGIA",
      "count": 1450
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 1437
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 1418
    },
    {
      "term": "INJURY",
      "count": 1343
    },
    {
      "term": "BLISTER",
      "count": 1309
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 1307
    },
    {
      "term": "STOMATITIS",
      "count": 1305
    },
    {
      "term": "INFLAMMATION",
      "count": 1266
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 1250
    },
    {
      "term": "INSOMNIA",
      "count": 1238
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 1235
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 1226
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 1208
    },
    {
      "term": "ARTHRITIS",
      "count": 1173
    },
    {
      "term": "PRESCRIBED OVERDOSE",
      "count": 1164
    },
    {
      "term": "SWOLLEN JOINT COUNT INCREASED",
      "count": 1163
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 1156
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 1141
    },
    {
      "term": "RED BLOOD CELL SEDIMENTATION RATE INCREASED",
      "count": 1129
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 1111
    },
    {
      "term": "FOLLICULITIS",
      "count": 1110
    },
    {
      "term": "ASTHENIA",
      "count": 1097
    },
    {
      "term": "SLEEP DISORDER",
      "count": 1083
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1059
    },
    {
      "term": "WHEEZING",
      "count": 1052
    },
    {
      "term": "SINUSITIS",
      "count": 1045
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 1036
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 1032
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 1028
    },
    {
      "term": "OEDEMA",
      "count": 997
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 973
    },
    {
      "term": "ASTHMA",
      "count": 963
    },
    {
      "term": "MUSCLE INJURY",
      "count": 957
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 953
    },
    {
      "term": "PULMONARY FIBROSIS",
      "count": 951
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 907
    },
    {
      "term": "CHEST PAIN",
      "count": 902
    },
    {
      "term": "ADVERSE EVENT",
      "count": 898
    }
  ]
}