{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "TREATMENT FAILURE",
      "count": 1107
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 956
    },
    {
      "term": "EYE IRRITATION",
      "count": 652
    },
    {
      "term": "EYE PAIN",
      "count": 611
    },
    {
      "term": "FATIGUE",
      "count": 541
    },
    {
      "term": "OFF LABEL USE",
      "count": 519
    },
    {
      "term": "VISION BLURRED",
      "count": 431
    },
    {
      "term": "DIZZINESS",
      "count": 412
    },
    {
      "term": "DIARRHOEA",
      "count": 407
    },
    {
      "term": "OCULAR HYPERAEMIA",
      "count": 405
    },
    {
      "term": "GLAUCOMA",
      "count": 395
    },
    {
      "term": "NAUSEA",
      "count": 377
    },
    {
      "term": "DYSPNOEA",
      "count": 374
    },
    {
      "term": "INTRAOCULAR PRESSURE INCREASED",
      "count": 372
    },
    {
      "term": "HEADACHE",
      "count": 351
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 315
    },
    {
      "term": "FALL",
      "count": 311
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 298
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 298
    },
    {
      "term": "VOMITING",
      "count": 297
    },
    {
      "term": "DEATH",
      "count": 296
    },
    {
      "term": "PAIN",
      "count": 292
    },
    {
      "term": "ASTHENIA",
      "count": 278
    },
    {
      "term": "HYPERTENSION",
      "count": 278
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 271
    },
    {
      "term": "PNEUMONIA",
      "count": 265
    },
    {
      "term": "EYE PRURITUS",
      "count": 261
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 243
    },
    {
      "term": "ARTHRALGIA",
      "count": 238
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 232
    },
    {
      "term": "RASH",
      "count": 229
    },
    {
      "term": "MALAISE",
      "count": 227
    },
    {
      "term": "PRURITUS",
      "count": 221
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 207
    },
    {
      "term": "CATARACT",
      "count": 204
    },
    {
      "term": "CONSTIPATION",
      "count": 200
    },
    {
      "term": "COUGH",
      "count": 191
    },
    {
      "term": "LACRIMATION INCREASED",
      "count": 183
    },
    {
      "term": "HYPOTENSION",
      "count": 179
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 178
    },
    {
      "term": "INSOMNIA",
      "count": 173
    },
    {
      "term": "DECREASED APPETITE",
      "count": 170
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 169
    },
    {
      "term": "DRY EYE",
      "count": 164
    },
    {
      "term": "SOMNOLENCE",
      "count": 160
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 158
    },
    {
      "term": "BRONCHITIS",
      "count": 157
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 156
    },
    {
      "term": "BACK PAIN",
      "count": 153
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 145
    },
    {
      "term": "BLINDNESS",
      "count": 144
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 144
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 142
    },
    {
      "term": "PYREXIA",
      "count": 136
    },
    {
      "term": "ERYTHEMA",
      "count": 135
    },
    {
      "term": "PRODUCT CONTAINER ISSUE",
      "count": 132
    },
    {
      "term": "ANXIETY",
      "count": 131
    },
    {
      "term": "BRADYCARDIA",
      "count": 127
    },
    {
      "term": "ALOPECIA",
      "count": 126
    },
    {
      "term": "DIVERTICULITIS",
      "count": 126
    },
    {
      "term": "DEPRESSION",
      "count": 124
    },
    {
      "term": "EYE SWELLING",
      "count": 124
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 120
    },
    {
      "term": "PRODUCT SUBSTITUTION ISSUE",
      "count": 120
    },
    {
      "term": "VISUAL ACUITY REDUCED",
      "count": 118
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 116
    },
    {
      "term": "COLITIS MICROSCOPIC",
      "count": 115
    },
    {
      "term": "DRUG INTERACTION",
      "count": 114
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 114
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 114
    },
    {
      "term": "ANAEMIA",
      "count": 113
    },
    {
      "term": "CHEST PAIN",
      "count": 113
    },
    {
      "term": "OCULAR DISCOMFORT",
      "count": 112
    },
    {
      "term": "SYNOVITIS",
      "count": 110
    },
    {
      "term": "EYE DISORDER",
      "count": 109
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 109
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 107
    },
    {
      "term": "DRY MOUTH",
      "count": 106
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 105
    },
    {
      "term": "SCIATICA",
      "count": 104
    },
    {
      "term": "PHOTOPHOBIA",
      "count": 103
    },
    {
      "term": "COVID-19",
      "count": 99
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 98
    },
    {
      "term": "FOREIGN BODY SENSATION IN EYES",
      "count": 98
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 98
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 97
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 96
    },
    {
      "term": "SYNCOPE",
      "count": 96
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 95
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 95
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 95
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 94
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 94
    },
    {
      "term": "INJECTION SITE REACTION",
      "count": 93
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 92
    },
    {
      "term": "HAND DEFORMITY",
      "count": 92
    },
    {
      "term": "THYROID DISORDER",
      "count": 91
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 90
    },
    {
      "term": "HEART RATE DECREASED",
      "count": 89
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 89
    }
  ]
}