{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "TREATMENT FAILURE",
      "count": 4064
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 2117
    },
    {
      "term": "FATIGUE",
      "count": 1186
    },
    {
      "term": "EYE IRRITATION",
      "count": 1160
    },
    {
      "term": "EYE PAIN",
      "count": 1132
    },
    {
      "term": "OFF LABEL USE",
      "count": 1105
    },
    {
      "term": "DIARRHOEA",
      "count": 963
    },
    {
      "term": "DIZZINESS",
      "count": 944
    },
    {
      "term": "VISION BLURRED",
      "count": 855
    },
    {
      "term": "NAUSEA",
      "count": 835
    },
    {
      "term": "DYSPNOEA",
      "count": 833
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 818
    },
    {
      "term": "INTRAOCULAR PRESSURE INCREASED",
      "count": 789
    },
    {
      "term": "HEADACHE",
      "count": 785
    },
    {
      "term": "FALL",
      "count": 762
    },
    {
      "term": "OCULAR HYPERAEMIA",
      "count": 749
    },
    {
      "term": "GLAUCOMA",
      "count": 721
    },
    {
      "term": "ASTHENIA",
      "count": 662
    },
    {
      "term": "DEATH",
      "count": 638
    },
    {
      "term": "PAIN",
      "count": 603
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 588
    },
    {
      "term": "VOMITING",
      "count": 575
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 566
    },
    {
      "term": "PNEUMONIA",
      "count": 504
    },
    {
      "term": "MALAISE",
      "count": 499
    },
    {
      "term": "ARTHRALGIA",
      "count": 492
    },
    {
      "term": "HYPERTENSION",
      "count": 486
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 469
    },
    {
      "term": "RASH",
      "count": 465
    },
    {
      "term": "PRURITUS",
      "count": 449
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 448
    },
    {
      "term": "COUGH",
      "count": 443
    },
    {
      "term": "EYE PRURITUS",
      "count": 441
    },
    {
      "term": "CONSTIPATION",
      "count": 440
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 435
    },
    {
      "term": "CATARACT",
      "count": 431
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 416
    },
    {
      "term": "DECREASED APPETITE",
      "count": 407
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 403
    },
    {
      "term": "HYPOTENSION",
      "count": 391
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 382
    },
    {
      "term": "INSOMNIA",
      "count": 369
    },
    {
      "term": "LACRIMATION INCREASED",
      "count": 356
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 352
    },
    {
      "term": "BACK PAIN",
      "count": 336
    },
    {
      "term": "SOMNOLENCE",
      "count": 336
    },
    {
      "term": "PYREXIA",
      "count": 330
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 329
    },
    {
      "term": "DRY EYE",
      "count": 320
    },
    {
      "term": "BRADYCARDIA",
      "count": 318
    },
    {
      "term": "ANAEMIA",
      "count": 303
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 303
    },
    {
      "term": "ANXIETY",
      "count": 296
    },
    {
      "term": "ERYTHEMA",
      "count": 296
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 296
    },
    {
      "term": "DRUG INTERACTION",
      "count": 295
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 289
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 289
    },
    {
      "term": "BLINDNESS",
      "count": 275
    },
    {
      "term": "VISUAL ACUITY REDUCED",
      "count": 272
    },
    {
      "term": "ALOPECIA",
      "count": 260
    },
    {
      "term": "DEPRESSION",
      "count": 260
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 259
    },
    {
      "term": "CHEST PAIN",
      "count": 252
    },
    {
      "term": "EYE SWELLING",
      "count": 251
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 251
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 245
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 240
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 239
    },
    {
      "term": "DRY MOUTH",
      "count": 235
    },
    {
      "term": "PRODUCT CONTAINER ISSUE",
      "count": 234
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 232
    },
    {
      "term": "MYALGIA",
      "count": 230
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 229
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 228
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 225
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 222
    },
    {
      "term": "SYNCOPE",
      "count": 216
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 214
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 211
    },
    {
      "term": "BRONCHITIS",
      "count": 208
    },
    {
      "term": "EYE DISORDER",
      "count": 208
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 207
    },
    {
      "term": "DEHYDRATION",
      "count": 205
    },
    {
      "term": "OCULAR DISCOMFORT",
      "count": 200
    },
    {
      "term": "PHOTOPHOBIA",
      "count": 200
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 198
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 197
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 197
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 196
    },
    {
      "term": "COVID-19",
      "count": 193
    },
    {
      "term": "BALANCE DISORDER",
      "count": 189
    },
    {
      "term": "RENAL FAILURE",
      "count": 186
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 185
    },
    {
      "term": "HALLUCINATION",
      "count": 184
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 177
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 175
    },
    {
      "term": "FOREIGN BODY SENSATION IN EYES",
      "count": 174
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 174
    },
    {
      "term": "JOINT SWELLING",
      "count": 172
    }
  ]
}