{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 611
    },
    {
      "term": "OFF LABEL USE",
      "count": 532
    },
    {
      "term": "NAUSEA",
      "count": 301
    },
    {
      "term": "SEPSIS",
      "count": 209
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 202
    },
    {
      "term": "VOMITING",
      "count": 200
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 196
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 181
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 172
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 157
    },
    {
      "term": "DIARRHOEA",
      "count": 152
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 150
    },
    {
      "term": "DEATH",
      "count": 149
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 141
    },
    {
      "term": "PYREXIA",
      "count": 138
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 135
    },
    {
      "term": "COAGULOPATHY",
      "count": 123
    },
    {
      "term": "DRUG INTERACTION",
      "count": 121
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 110
    },
    {
      "term": "PANCREATITIS ACUTE",
      "count": 107
    },
    {
      "term": "PNEUMONIA",
      "count": 101
    },
    {
      "term": "ANAEMIA",
      "count": 96
    },
    {
      "term": "RENAL FAILURE",
      "count": 95
    },
    {
      "term": "KLEBSIELLA INFECTION",
      "count": 91
    },
    {
      "term": "HYPOFIBRINOGENAEMIA",
      "count": 87
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 86
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 84
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 84
    },
    {
      "term": "HYPOTENSION",
      "count": 83
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 83
    },
    {
      "term": "NEUTROPENIA",
      "count": 74
    },
    {
      "term": "FATIGUE",
      "count": 72
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 69
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 68
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 68
    },
    {
      "term": "RASH",
      "count": 65
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 64
    },
    {
      "term": "DECREASED APPETITE",
      "count": 63
    },
    {
      "term": "PANCREATITIS",
      "count": 63
    },
    {
      "term": "DYSPNOEA",
      "count": 62
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 60
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 59
    },
    {
      "term": "PSEUDOMONAS INFECTION",
      "count": 58
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 57
    },
    {
      "term": "INFECTION",
      "count": 55
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 54
    },
    {
      "term": "BLOOD FIBRINOGEN DECREASED",
      "count": 54
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 54
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 54
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 53
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 53
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 52
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 52
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 52
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 51
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 51
    },
    {
      "term": "MALAISE",
      "count": 51
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 51
    },
    {
      "term": "ACINETOBACTER INFECTION",
      "count": 50
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 50
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 48
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 48
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 48
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 47
    },
    {
      "term": "MYCOBACTERIUM ABSCESSUS INFECTION",
      "count": 47
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 47
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 46
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 45
    },
    {
      "term": "LIVER INJURY",
      "count": 45
    },
    {
      "term": "MULTIPLE-DRUG RESISTANCE",
      "count": 45
    },
    {
      "term": "PANCYTOPENIA",
      "count": 44
    },
    {
      "term": "CARDIAC ARREST",
      "count": 43
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 43
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 43
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 40
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 40
    },
    {
      "term": "ASTHENIA",
      "count": 39
    },
    {
      "term": "BLOOD UREA INCREASED",
      "count": 39
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 39
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 38
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 37
    },
    {
      "term": "DEAFNESS",
      "count": 37
    },
    {
      "term": "DYSBIOSIS",
      "count": 37
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 37
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 36
    },
    {
      "term": "BACTERAEMIA",
      "count": 36
    },
    {
      "term": "COUGH",
      "count": 36
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 36
    },
    {
      "term": "LEUKOPENIA",
      "count": 36
    },
    {
      "term": "OTOTOXICITY",
      "count": 36
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 36
    },
    {
      "term": "ESCHERICHIA INFECTION",
      "count": 35
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 34
    },
    {
      "term": "HYPOGLYCAEMIA",
      "count": 34
    },
    {
      "term": "ABSCESS",
      "count": 32
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 32
    },
    {
      "term": "LACTIC ACIDOSIS",
      "count": 32
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 31
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 31
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 31
    }
  ]
}