{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "PLASMA CELL MYELOMA",
      "count": 1303
    },
    {
      "term": "OFF LABEL USE",
      "count": 1064
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 977
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 819
    },
    {
      "term": "PNEUMONIA",
      "count": 782
    },
    {
      "term": "DEATH",
      "count": 769
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 662
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 662
    },
    {
      "term": "ANAEMIA",
      "count": 633
    },
    {
      "term": "NEUTROPENIA",
      "count": 607
    },
    {
      "term": "PYREXIA",
      "count": 567
    },
    {
      "term": "INFECTION",
      "count": 563
    },
    {
      "term": "FATIGUE",
      "count": 515
    },
    {
      "term": "DIARRHOEA",
      "count": 463
    },
    {
      "term": "SEPSIS",
      "count": 439
    },
    {
      "term": "CONSTIPATION",
      "count": 417
    },
    {
      "term": "NAUSEA",
      "count": 408
    },
    {
      "term": "OSTEONECROSIS",
      "count": 401
    },
    {
      "term": "ASTHENIA",
      "count": 396
    },
    {
      "term": "DYSPNOEA",
      "count": 390
    },
    {
      "term": "PANCYTOPENIA",
      "count": 358
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 355
    },
    {
      "term": "PAIN",
      "count": 338
    },
    {
      "term": "RENAL FAILURE",
      "count": 331
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 312
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 311
    },
    {
      "term": "RASH",
      "count": 298
    },
    {
      "term": "VOMITING",
      "count": 293
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 288
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 285
    },
    {
      "term": "POLYNEUROPATHY",
      "count": 283
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 273
    },
    {
      "term": "BONE DISORDER",
      "count": 270
    },
    {
      "term": "PLASMA CELL MYELOMA RECURRENT",
      "count": 255
    },
    {
      "term": "DIZZINESS",
      "count": 244
    },
    {
      "term": "HYPOTENSION",
      "count": 244
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 241
    },
    {
      "term": "MULTIPLE MYELOMA",
      "count": 234
    },
    {
      "term": "HYPERTENSION",
      "count": 229
    },
    {
      "term": "BACK PAIN",
      "count": 228
    },
    {
      "term": "HERPES ZOSTER",
      "count": 226
    },
    {
      "term": "FALL",
      "count": 222
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 216
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 208
    },
    {
      "term": "ARTHRALGIA",
      "count": 205
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 200
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 198
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 195
    },
    {
      "term": "PARAESTHESIA",
      "count": 193
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 190
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 189
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 185
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 184
    },
    {
      "term": "HEADACHE",
      "count": 182
    },
    {
      "term": "OSTEOMYELITIS",
      "count": 182
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 180
    },
    {
      "term": "PLASMACYTOMA",
      "count": 180
    },
    {
      "term": "PAIN IN JAW",
      "count": 178
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 177
    },
    {
      "term": "DECREASED APPETITE",
      "count": 175
    },
    {
      "term": "ANXIETY",
      "count": 174
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 173
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 171
    },
    {
      "term": "TOOTH EXTRACTION",
      "count": 171
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 170
    },
    {
      "term": "SOMNOLENCE",
      "count": 170
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 168
    },
    {
      "term": "LEUKOPENIA",
      "count": 167
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 167
    },
    {
      "term": "COUGH",
      "count": 165
    },
    {
      "term": "COVID-19",
      "count": 165
    },
    {
      "term": "SYNCOPE",
      "count": 165
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 164
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 164
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 151
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 151
    },
    {
      "term": "CHEST PAIN",
      "count": 150
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 145
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 144
    },
    {
      "term": "DEHYDRATION",
      "count": 144
    },
    {
      "term": "LYMPHOPENIA",
      "count": 142
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 140
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 139
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 139
    },
    {
      "term": "DEPRESSION",
      "count": 137
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 134
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 133
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 132
    },
    {
      "term": "BONE LESION",
      "count": 131
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 130
    },
    {
      "term": "TREMOR",
      "count": 127
    },
    {
      "term": "MALAISE",
      "count": 125
    },
    {
      "term": "BONE PAIN",
      "count": 124
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 124
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 122
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 120
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 120
    },
    {
      "term": "PERIPHERAL SENSORY NEUROPATHY",
      "count": 119
    },
    {
      "term": "SINUSITIS",
      "count": 118
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 118
    }
  ]
}