{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DISEASE PROGRESSION",
      "count": 153
    },
    {
      "term": "PNEUMONIA",
      "count": 135
    },
    {
      "term": "DIARRHOEA",
      "count": 134
    },
    {
      "term": "VOMITING",
      "count": 129
    },
    {
      "term": "FATIGUE",
      "count": 128
    },
    {
      "term": "DEHYDRATION",
      "count": 126
    },
    {
      "term": "ANAEMIA",
      "count": 122
    },
    {
      "term": "NAUSEA",
      "count": 112
    },
    {
      "term": "PYREXIA",
      "count": 111
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 109
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 109
    },
    {
      "term": "STOMATITIS",
      "count": 107
    },
    {
      "term": "DYSPNOEA",
      "count": 101
    },
    {
      "term": "NEUTROPENIA",
      "count": 95
    },
    {
      "term": "DEATH",
      "count": 82
    },
    {
      "term": "OFF LABEL USE",
      "count": 80
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 75
    },
    {
      "term": "PNEUMONITIS",
      "count": 71
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 70
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 66
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 65
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 63
    },
    {
      "term": "ASTHENIA",
      "count": 63
    },
    {
      "term": "DECREASED APPETITE",
      "count": 62
    },
    {
      "term": "SEPSIS",
      "count": 62
    },
    {
      "term": "HYPERTENSION",
      "count": 56
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 54
    },
    {
      "term": "RENAL CELL CARCINOMA",
      "count": 51
    },
    {
      "term": "EPISTAXIS",
      "count": 47
    },
    {
      "term": "HEADACHE",
      "count": 46
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 45
    },
    {
      "term": "RENAL FAILURE",
      "count": 45
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 42
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 41
    },
    {
      "term": "HYPERTRIGLYCERIDAEMIA",
      "count": 41
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 40
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 40
    },
    {
      "term": "PAIN",
      "count": 40
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 39
    },
    {
      "term": "HYPOPHOSPHATAEMIA",
      "count": 38
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 38
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 38
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 37
    },
    {
      "term": "CONSTIPATION",
      "count": 37
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 36
    },
    {
      "term": "HYPOTENSION",
      "count": 34
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 33
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 33
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 32
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 32
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 30
    },
    {
      "term": "PROTEINURIA",
      "count": 30
    },
    {
      "term": "RASH",
      "count": 30
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 29
    },
    {
      "term": "COUGH",
      "count": 28
    },
    {
      "term": "HYPOXIA",
      "count": 28
    },
    {
      "term": "LYMPHOPENIA",
      "count": 28
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 28
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 27
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 27
    },
    {
      "term": "INFECTION",
      "count": 27
    },
    {
      "term": "LEUKOPENIA",
      "count": 27
    },
    {
      "term": "METASTATIC RENAL CELL CARCINOMA",
      "count": 27
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 25
    },
    {
      "term": "COLITIS",
      "count": 25
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 25
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 25
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 25
    },
    {
      "term": "CARDIAC ARREST",
      "count": 24
    },
    {
      "term": "SYNCOPE",
      "count": 24
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 23
    },
    {
      "term": "HYPERCHOLESTEROLAEMIA",
      "count": 23
    },
    {
      "term": "MALAISE",
      "count": 23
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 23
    },
    {
      "term": "ASCITES",
      "count": 22
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 22
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 22
    },
    {
      "term": "OVERDOSE",
      "count": 22
    },
    {
      "term": "CHILLS",
      "count": 21
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 21
    },
    {
      "term": "PERICARDIAL EFFUSION",
      "count": 21
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 20
    },
    {
      "term": "NEOPLASM MALIGNANT",
      "count": 20
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 20
    },
    {
      "term": "UPPER GASTROINTESTINAL HAEMORRHAGE",
      "count": 20
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 19
    },
    {
      "term": "DIZZINESS",
      "count": 19
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 19
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 18
    },
    {
      "term": "BACK PAIN",
      "count": 18
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 18
    },
    {
      "term": "LUNG INFECTION",
      "count": 18
    },
    {
      "term": "SUDDEN DEATH",
      "count": 18
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 17
    },
    {
      "term": "PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME",
      "count": 17
    },
    {
      "term": "PULMONARY HAEMORRHAGE",
      "count": 17
    },
    {
      "term": "THROMBOSIS",
      "count": 17
    },
    {
      "term": "HAEMATURIA",
      "count": 16
    },
    {
      "term": "HYPOALBUMINAEMIA",
      "count": 16
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 16
    }
  ]
}