{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DYSPNOEA",
      "count": 8957
    },
    {
      "term": "FATIGUE",
      "count": 7307
    },
    {
      "term": "NAUSEA",
      "count": 6855
    },
    {
      "term": "DIARRHOEA",
      "count": 6449
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 5713
    },
    {
      "term": "DIZZINESS",
      "count": 5573
    },
    {
      "term": "HEADACHE",
      "count": 5340
    },
    {
      "term": "OFF LABEL USE",
      "count": 5049
    },
    {
      "term": "HYPOTENSION",
      "count": 4840
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 4838
    },
    {
      "term": "FALL",
      "count": 4264
    },
    {
      "term": "ASTHENIA",
      "count": 4156
    },
    {
      "term": "VOMITING",
      "count": 4154
    },
    {
      "term": "DEATH",
      "count": 4131
    },
    {
      "term": "PAIN",
      "count": 3801
    },
    {
      "term": "COUGH",
      "count": 3675
    },
    {
      "term": "MALAISE",
      "count": 3651
    },
    {
      "term": "PNEUMONIA",
      "count": 3648
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 3627
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 3601
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 3172
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 3006
    },
    {
      "term": "ANAEMIA",
      "count": 2928
    },
    {
      "term": "ARTHRALGIA",
      "count": 2922
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 2909
    },
    {
      "term": "DRUG INTERACTION",
      "count": 2766
    },
    {
      "term": "RENAL FAILURE",
      "count": 2764
    },
    {
      "term": "DEHYDRATION",
      "count": 2683
    },
    {
      "term": "DECREASED APPETITE",
      "count": 2638
    },
    {
      "term": "PRURITUS",
      "count": 2525
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 2458
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 2441
    },
    {
      "term": "PYREXIA",
      "count": 2438
    },
    {
      "term": "RASH",
      "count": 2381
    },
    {
      "term": "HYPERTENSION",
      "count": 2342
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 2313
    },
    {
      "term": "CHEST PAIN",
      "count": 2309
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 2280
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 2191
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 2143
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 2123
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 2092
    },
    {
      "term": "BACK PAIN",
      "count": 2053
    },
    {
      "term": "CONSTIPATION",
      "count": 2040
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 2027
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 1984
    },
    {
      "term": "INSOMNIA",
      "count": 1940
    },
    {
      "term": "ANXIETY",
      "count": 1917
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 1819
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 1801
    },
    {
      "term": "FLUID RETENTION",
      "count": 1738
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 1695
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 1692
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 1677
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 1675
    },
    {
      "term": "SYNCOPE",
      "count": 1652
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 1606
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 1586
    },
    {
      "term": "SOMNOLENCE",
      "count": 1523
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 1517
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 1502
    },
    {
      "term": "DEPRESSION",
      "count": 1494
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 1448
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 1437
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 1421
    },
    {
      "term": "ASCITES",
      "count": 1408
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 1400
    },
    {
      "term": "OEDEMA",
      "count": 1383
    },
    {
      "term": "COVID-19",
      "count": 1380
    },
    {
      "term": "CARDIAC DISORDER",
      "count": 1378
    },
    {
      "term": "PALPITATIONS",
      "count": 1376
    },
    {
      "term": "SEPSIS",
      "count": 1336
    },
    {
      "term": "MYALGIA",
      "count": 1328
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 1325
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 1317
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 1312
    },
    {
      "term": "EPISTAXIS",
      "count": 1285
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 1276
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1253
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 1236
    },
    {
      "term": "BRADYCARDIA",
      "count": 1227
    },
    {
      "term": "DYSPNOEA EXERTIONAL",
      "count": 1222
    },
    {
      "term": "ALOPECIA",
      "count": 1217
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 1217
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 1204
    },
    {
      "term": "TREMOR",
      "count": 1178
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 1162
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 1149
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 1114
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 1109
    },
    {
      "term": "ERYTHEMA",
      "count": 1086
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 1084
    },
    {
      "term": "HOSPITALISATION",
      "count": 1082
    },
    {
      "term": "CONTUSION",
      "count": 1080
    },
    {
      "term": "PULMONARY HYPERTENSION",
      "count": 1079
    },
    {
      "term": "ASTHMA",
      "count": 1073
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 1071
    },
    {
      "term": "CARDIAC ARREST",
      "count": 1067
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 1061
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 1041
    }
  ]
}