{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 1948
    },
    {
      "term": "NAUSEA",
      "count": 1357
    },
    {
      "term": "PYREXIA",
      "count": 1305
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1158
    },
    {
      "term": "VOMITING",
      "count": 1146
    },
    {
      "term": "DIARRHOEA",
      "count": 961
    },
    {
      "term": "ANAEMIA",
      "count": 951
    },
    {
      "term": "DYSPNOEA",
      "count": 917
    },
    {
      "term": "FATIGUE",
      "count": 874
    },
    {
      "term": "PNEUMONIA",
      "count": 814
    },
    {
      "term": "CONSTIPATION",
      "count": 813
    },
    {
      "term": "PAIN",
      "count": 781
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 743
    },
    {
      "term": "HEADACHE",
      "count": 724
    },
    {
      "term": "RASH",
      "count": 689
    },
    {
      "term": "SEPSIS",
      "count": 662
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 650
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 639
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 638
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 625
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 617
    },
    {
      "term": "DEATH",
      "count": 615
    },
    {
      "term": "NEUTROPENIA",
      "count": 597
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 583
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 553
    },
    {
      "term": "DECREASED APPETITE",
      "count": 549
    },
    {
      "term": "ASTHENIA",
      "count": 542
    },
    {
      "term": "MALAISE",
      "count": 538
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 525
    },
    {
      "term": "HYPERTENSION",
      "count": 521
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 466
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 465
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 455
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 428
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 404
    },
    {
      "term": "ARTHRALGIA",
      "count": 402
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 401
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 399
    },
    {
      "term": "DIZZINESS",
      "count": 385
    },
    {
      "term": "COUGH",
      "count": 379
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 374
    },
    {
      "term": "ERYTHEMA",
      "count": 374
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 373
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 367
    },
    {
      "term": "BACK PAIN",
      "count": 365
    },
    {
      "term": "INFECTION",
      "count": 361
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 360
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 360
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 359
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 358
    },
    {
      "term": "ASCITES",
      "count": 353
    },
    {
      "term": "PRURITUS",
      "count": 344
    },
    {
      "term": "SOMNOLENCE",
      "count": 335
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 327
    },
    {
      "term": "ASTHMA",
      "count": 320
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 318
    },
    {
      "term": "ALOPECIA",
      "count": 317
    },
    {
      "term": "HYPOTENSION",
      "count": 310
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 303
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 300
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 295
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 289
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 289
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 286
    },
    {
      "term": "SWELLING",
      "count": 286
    },
    {
      "term": "STRESS",
      "count": 284
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 282
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 279
    },
    {
      "term": "FALL",
      "count": 276
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 276
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 276
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 272
    },
    {
      "term": "INSOMNIA",
      "count": 270
    },
    {
      "term": "STOMATITIS",
      "count": 270
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 267
    },
    {
      "term": "CARDIOGENIC SHOCK",
      "count": 265
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 264
    },
    {
      "term": "JOINT SWELLING",
      "count": 264
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 262
    },
    {
      "term": "ANXIETY",
      "count": 261
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 256
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 255
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 254
    },
    {
      "term": "APPENDICITIS",
      "count": 250
    },
    {
      "term": "LEUKOPENIA",
      "count": 250
    },
    {
      "term": "DEHYDRATION",
      "count": 248
    },
    {
      "term": "COVID-19",
      "count": 246
    },
    {
      "term": "PANCYTOPENIA",
      "count": 243
    },
    {
      "term": "SLEEP DISORDER",
      "count": 243
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 243
    },
    {
      "term": "DRY MOUTH",
      "count": 239
    },
    {
      "term": "OVERDOSE",
      "count": 236
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 235
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 234
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 233
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 233
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 233
    },
    {
      "term": "CHEST PAIN",
      "count": 229
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 229
    },
    {
      "term": "APPENDICOLITH",
      "count": 228
    }
  ]
}