{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 698
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 681
    },
    {
      "term": "JOINT SWELLING",
      "count": 627
    },
    {
      "term": "PAIN",
      "count": 598
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 540
    },
    {
      "term": "ALOPECIA",
      "count": 535
    },
    {
      "term": "PEMPHIGUS",
      "count": 535
    },
    {
      "term": "FATIGUE",
      "count": 532
    },
    {
      "term": "RASH",
      "count": 532
    },
    {
      "term": "SYNOVITIS",
      "count": 522
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 521
    },
    {
      "term": "HAND DEFORMITY",
      "count": 520
    },
    {
      "term": "GLOSSODYNIA",
      "count": 516
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 510
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 504
    },
    {
      "term": "OFF LABEL USE",
      "count": 495
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 492
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 487
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 486
    },
    {
      "term": "PERICARDITIS",
      "count": 485
    },
    {
      "term": "WOUND",
      "count": 479
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 472
    },
    {
      "term": "SWELLING",
      "count": 468
    },
    {
      "term": "ARTHRALGIA",
      "count": 465
    },
    {
      "term": "ARTHROPATHY",
      "count": 465
    },
    {
      "term": "DISCOMFORT",
      "count": 424
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 412
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 403
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 392
    },
    {
      "term": "NAUSEA",
      "count": 368
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 360
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 354
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 348
    },
    {
      "term": "HEADACHE",
      "count": 343
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 323
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 320
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 315
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 310
    },
    {
      "term": "BLISTER",
      "count": 305
    },
    {
      "term": "HYPERTENSION",
      "count": 301
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 299
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 294
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 288
    },
    {
      "term": "INJURY",
      "count": 282
    },
    {
      "term": "PNEUMONIA",
      "count": 280
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 267
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 264
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 261
    },
    {
      "term": "STOMATITIS",
      "count": 257
    },
    {
      "term": "URTICARIA",
      "count": 252
    },
    {
      "term": "DIARRHOEA",
      "count": 251
    },
    {
      "term": "LIVER INJURY",
      "count": 251
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 249
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 245
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 242
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 242
    },
    {
      "term": "VOMITING",
      "count": 240
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 239
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 238
    },
    {
      "term": "DYSPNOEA",
      "count": 232
    },
    {
      "term": "FIBROMYALGIA",
      "count": 227
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 226
    },
    {
      "term": "MALAISE",
      "count": 226
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 223
    },
    {
      "term": "FOLLICULITIS",
      "count": 223
    },
    {
      "term": "PYREXIA",
      "count": 223
    },
    {
      "term": "SLEEP DISORDER",
      "count": 222
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 217
    },
    {
      "term": "PRURITUS",
      "count": 215
    },
    {
      "term": "SWOLLEN JOINT COUNT INCREASED",
      "count": 215
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 213
    },
    {
      "term": "MUSCLE INJURY",
      "count": 213
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 211
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 211
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 210
    },
    {
      "term": "INFECTION",
      "count": 208
    },
    {
      "term": "SINUSITIS",
      "count": 208
    },
    {
      "term": "HIP ARTHROPLASTY",
      "count": 206
    },
    {
      "term": "OEDEMA",
      "count": 203
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 201
    },
    {
      "term": "DECREASED APPETITE",
      "count": 195
    },
    {
      "term": "DYSPEPSIA",
      "count": 193
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 192
    },
    {
      "term": "KNEE ARTHROPLASTY",
      "count": 192
    },
    {
      "term": "WHEEZING",
      "count": 192
    },
    {
      "term": "DIZZINESS",
      "count": 181
    },
    {
      "term": "MIGRAINE",
      "count": 179
    },
    {
      "term": "CONTUSION",
      "count": 178
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 171
    },
    {
      "term": "HYPERCHOLESTEROLAEMIA",
      "count": 171
    },
    {
      "term": "GRIP STRENGTH DECREASED",
      "count": 170
    },
    {
      "term": "PULMONARY FIBROSIS",
      "count": 168
    },
    {
      "term": "DEPRESSION",
      "count": 167
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 167
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 163
    },
    {
      "term": "ASTHENIA",
      "count": 161
    },
    {
      "term": "INFLAMMATION",
      "count": 159
    },
    {
      "term": "CHEST PAIN",
      "count": 157
    },
    {
      "term": "GAIT INABILITY",
      "count": 157
    },
    {
      "term": "WOUND INFECTION",
      "count": 157
    }
  ]
}