{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "HYPOTENSION",
      "count": 777
    },
    {
      "term": "DYSPNOEA",
      "count": 556
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 515
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 432
    },
    {
      "term": "DIZZINESS",
      "count": 416
    },
    {
      "term": "DEATH",
      "count": 391
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 364
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 333
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 325
    },
    {
      "term": "OFF LABEL USE",
      "count": 287
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 277
    },
    {
      "term": "ASTHENIA",
      "count": 264
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 250
    },
    {
      "term": "FATIGUE",
      "count": 244
    },
    {
      "term": "CARDIAC ARREST",
      "count": 210
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 204
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 193
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 190
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 188
    },
    {
      "term": "COUGH",
      "count": 186
    },
    {
      "term": "CARDIAC FAILURE CHRONIC",
      "count": 180
    },
    {
      "term": "EJECTION FRACTION DECREASED",
      "count": 173
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 173
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 172
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 170
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 168
    },
    {
      "term": "PRESCRIBED UNDERDOSE",
      "count": 166
    },
    {
      "term": "CHEST PAIN",
      "count": 163
    },
    {
      "term": "DIARRHOEA",
      "count": 157
    },
    {
      "term": "ANAEMIA",
      "count": 151
    },
    {
      "term": "NAUSEA",
      "count": 151
    },
    {
      "term": "PNEUMONIA",
      "count": 144
    },
    {
      "term": "DRUG INTERACTION",
      "count": 138
    },
    {
      "term": "HYPERTENSION",
      "count": 136
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 129
    },
    {
      "term": "VENTRICULAR TACHYCARDIA",
      "count": 129
    },
    {
      "term": "PALPITATIONS",
      "count": 123
    },
    {
      "term": "MITRAL VALVE INCOMPETENCE",
      "count": 122
    },
    {
      "term": "DYSPNOEA EXERTIONAL",
      "count": 113
    },
    {
      "term": "GLOMERULAR FILTRATION RATE DECREASED",
      "count": 113
    },
    {
      "term": "N-TERMINAL PROHORMONE BRAIN NATRIURETIC PEPTIDE INCREASED",
      "count": 113
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 112
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 109
    },
    {
      "term": "VOMITING",
      "count": 108
    },
    {
      "term": "HEADACHE",
      "count": 107
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 106
    },
    {
      "term": "SYNCOPE",
      "count": 101
    },
    {
      "term": "FALL",
      "count": 100
    },
    {
      "term": "RENAL FAILURE",
      "count": 100
    },
    {
      "term": "DECREASED APPETITE",
      "count": 97
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 97
    },
    {
      "term": "CARDIAC DISORDER",
      "count": 93
    },
    {
      "term": "ARRHYTHMIA",
      "count": 92
    },
    {
      "term": "EXERCISE TOLERANCE DECREASED",
      "count": 89
    },
    {
      "term": "ANGIOEDEMA",
      "count": 87
    },
    {
      "term": "BLOOD POTASSIUM INCREASED",
      "count": 86
    },
    {
      "term": "COVID-19",
      "count": 86
    },
    {
      "term": "TACHYCARDIA",
      "count": 82
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 81
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 79
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 75
    },
    {
      "term": "DEHYDRATION",
      "count": 75
    },
    {
      "term": "UNDERDOSE",
      "count": 75
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 73
    },
    {
      "term": "TACHYPNOEA",
      "count": 72
    },
    {
      "term": "CARDIOMYOPATHY",
      "count": 71
    },
    {
      "term": "PRURITUS",
      "count": 70
    },
    {
      "term": "PYREXIA",
      "count": 69
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 68
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 68
    },
    {
      "term": "OEDEMA",
      "count": 68
    },
    {
      "term": "PULMONARY CONGESTION",
      "count": 68
    },
    {
      "term": "VENTRICULAR EXTRASYSTOLES",
      "count": 67
    },
    {
      "term": "MALAISE",
      "count": 64
    },
    {
      "term": "TRICUSPID VALVE INCOMPETENCE",
      "count": 64
    },
    {
      "term": "BRADYCARDIA",
      "count": 62
    },
    {
      "term": "CARDIOGENIC SHOCK",
      "count": 62
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 62
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 60
    },
    {
      "term": "INSOMNIA",
      "count": 58
    },
    {
      "term": "PRODUCT PRESCRIBING ERROR",
      "count": 58
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 57
    },
    {
      "term": "RASH",
      "count": 57
    },
    {
      "term": "CONGESTIVE CARDIOMYOPATHY",
      "count": 56
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 56
    },
    {
      "term": "HEART RATE DECREASED",
      "count": 56
    },
    {
      "term": "PRESYNCOPE",
      "count": 56
    },
    {
      "term": "VENTRICULAR HYPOKINESIA",
      "count": 56
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 55
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 54
    },
    {
      "term": "CARDIAC FAILURE ACUTE",
      "count": 53
    },
    {
      "term": "PAIN",
      "count": 53
    },
    {
      "term": "ANGINA PECTORIS",
      "count": 52
    },
    {
      "term": "ERYTHEMA",
      "count": 52
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 52
    },
    {
      "term": "LACTIC ACIDOSIS",
      "count": 52
    },
    {
      "term": "OBESITY",
      "count": 49
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 49
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 48
    },
    {
      "term": "ORTHOPNOEA",
      "count": 48
    }
  ]
}