{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DISEASE PROGRESSION",
      "count": 776
    },
    {
      "term": "DEATH",
      "count": 497
    },
    {
      "term": "DIARRHOEA",
      "count": 352
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 346
    },
    {
      "term": "NEUTROPENIA",
      "count": 278
    },
    {
      "term": "OFF LABEL USE",
      "count": 245
    },
    {
      "term": "FATIGUE",
      "count": 205
    },
    {
      "term": "WEIGHT FLUCTUATION",
      "count": 186
    },
    {
      "term": "ASTHENIA",
      "count": 184
    },
    {
      "term": "NAUSEA",
      "count": 173
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 167
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 142
    },
    {
      "term": "VOMITING",
      "count": 111
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 108
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 107
    },
    {
      "term": "ALOPECIA",
      "count": 104
    },
    {
      "term": "MALAISE",
      "count": 101
    },
    {
      "term": "CONSTIPATION",
      "count": 100
    },
    {
      "term": "ANAEMIA",
      "count": 98
    },
    {
      "term": "PYREXIA",
      "count": 91
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 89
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 88
    },
    {
      "term": "DYSPNOEA",
      "count": 82
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 78
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 76
    },
    {
      "term": "SEPSIS",
      "count": 76
    },
    {
      "term": "PAIN",
      "count": 75
    },
    {
      "term": "COLITIS",
      "count": 73
    },
    {
      "term": "HYPOTENSION",
      "count": 73
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 73
    },
    {
      "term": "COVID-19",
      "count": 68
    },
    {
      "term": "DECREASED APPETITE",
      "count": 66
    },
    {
      "term": "HYPERTENSION",
      "count": 65
    },
    {
      "term": "PNEUMONIA",
      "count": 64
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 61
    },
    {
      "term": "COUGH",
      "count": 55
    },
    {
      "term": "HEADACHE",
      "count": 53
    },
    {
      "term": "DIZZINESS",
      "count": 50
    },
    {
      "term": "RASH",
      "count": 46
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 42
    },
    {
      "term": "NEUTROPENIC COLITIS",
      "count": 42
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 41
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 41
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 39
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 38
    },
    {
      "term": "METASTASES TO CENTRAL NERVOUS SYSTEM",
      "count": 37
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 37
    },
    {
      "term": "DEHYDRATION",
      "count": 36
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 36
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 36
    },
    {
      "term": "SOMNOLENCE",
      "count": 35
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 33
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 31
    },
    {
      "term": "BACK PAIN",
      "count": 30
    },
    {
      "term": "GENERAL PHYSICAL CONDITION ABNORMAL",
      "count": 30
    },
    {
      "term": "METASTASES TO BONE",
      "count": 29
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 29
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 29
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 28
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 28
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 28
    },
    {
      "term": "TRIPLE NEGATIVE BREAST CANCER",
      "count": 28
    },
    {
      "term": "INFECTION",
      "count": 27
    },
    {
      "term": "LEUKOPENIA",
      "count": 27
    },
    {
      "term": "ARTHRALGIA",
      "count": 26
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 26
    },
    {
      "term": "NEUTROPHIL COUNT ABNORMAL",
      "count": 26
    },
    {
      "term": "DYSPHAGIA",
      "count": 25
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 25
    },
    {
      "term": "PANCYTOPENIA",
      "count": 25
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 24
    },
    {
      "term": "INTENTIONAL DOSE OMISSION",
      "count": 24
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 24
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 24
    },
    {
      "term": "PNEUMONITIS",
      "count": 24
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 24
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 23
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 22
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 22
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 22
    },
    {
      "term": "SARS-COV-2 TEST POSITIVE",
      "count": 22
    },
    {
      "term": "OROPHARYNGEAL PAIN",
      "count": 21
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 20
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 20
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 20
    },
    {
      "term": "PRURITUS",
      "count": 20
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 20
    },
    {
      "term": "FEBRILE BONE MARROW APLASIA",
      "count": 19
    },
    {
      "term": "ILLNESS",
      "count": 19
    },
    {
      "term": "RED BLOOD CELL COUNT DECREASED",
      "count": 19
    },
    {
      "term": "ANXIETY",
      "count": 18
    },
    {
      "term": "ENTERITIS",
      "count": 18
    },
    {
      "term": "PRODUCTIVE COUGH",
      "count": 18
    },
    {
      "term": "RENAL FAILURE",
      "count": 18
    },
    {
      "term": "ASCITES",
      "count": 17
    },
    {
      "term": "CHILLS",
      "count": 17
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 17
    },
    {
      "term": "HYPOTHYROIDISM",
      "count": 17
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 17
    },
    {
      "term": "SEIZURE",
      "count": 17
    }
  ]
}