{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 704
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 633
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 586
    },
    {
      "term": "HYPOTENSION",
      "count": 506
    },
    {
      "term": "CARDIAC ARREST",
      "count": 350
    },
    {
      "term": "TACHYCARDIA",
      "count": 211
    },
    {
      "term": "BRADYCARDIA",
      "count": 204
    },
    {
      "term": "BRONCHOSPASM",
      "count": 204
    },
    {
      "term": "RASH",
      "count": 177
    },
    {
      "term": "DRUG INTERACTION",
      "count": 175
    },
    {
      "term": "URTICARIA",
      "count": 157
    },
    {
      "term": "OFF LABEL USE",
      "count": 152
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 134
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 130
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 117
    },
    {
      "term": "HYPOXIA",
      "count": 111
    },
    {
      "term": "CIRCULATORY COLLAPSE",
      "count": 110
    },
    {
      "term": "ERYTHEMA",
      "count": 101
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 97
    },
    {
      "term": "PAIN",
      "count": 91
    },
    {
      "term": "DYSPNOEA",
      "count": 86
    },
    {
      "term": "NEUROMUSCULAR BLOCK PROLONGED",
      "count": 86
    },
    {
      "term": "RENAL FAILURE",
      "count": 85
    },
    {
      "term": "HYPERTHERMIA MALIGNANT",
      "count": 82
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 82
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 77
    },
    {
      "term": "RESPIRATORY ARREST",
      "count": 72
    },
    {
      "term": "RECURRENCE OF NEUROMUSCULAR BLOCKADE",
      "count": 70
    },
    {
      "term": "VENTRICULAR TACHYCARDIA",
      "count": 70
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 69
    },
    {
      "term": "DELAYED RECOVERY FROM ANAESTHESIA",
      "count": 68
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 63
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 62
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 62
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 61
    },
    {
      "term": "VENTRICULAR FIBRILLATION",
      "count": 61
    },
    {
      "term": "ANXIETY",
      "count": 60
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 60
    },
    {
      "term": "PARALYSIS",
      "count": 60
    },
    {
      "term": "PYREXIA",
      "count": 59
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 57
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 57
    },
    {
      "term": "STRESS CARDIOMYOPATHY",
      "count": 57
    },
    {
      "term": "HYPERTENSION",
      "count": 56
    },
    {
      "term": "HYPOVENTILATION",
      "count": 56
    },
    {
      "term": "ANGIOEDEMA",
      "count": 55
    },
    {
      "term": "PREMATURE BABY",
      "count": 54
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 52
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 51
    },
    {
      "term": "UNEVALUABLE EVENT",
      "count": 51
    },
    {
      "term": "DRUG EFFECT DECREASED",
      "count": 50
    },
    {
      "term": "HAEMODYNAMIC INSTABILITY",
      "count": 50
    },
    {
      "term": "OVERDOSE",
      "count": 49
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 48
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 48
    },
    {
      "term": "PULSELESS ELECTRICAL ACTIVITY",
      "count": 48
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 47
    },
    {
      "term": "FEAR",
      "count": 45
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 45
    },
    {
      "term": "INJURY",
      "count": 44
    },
    {
      "term": "ANAESTHETIC COMPLICATION",
      "count": 43
    },
    {
      "term": "POST PROCEDURAL COMPLICATION",
      "count": 43
    },
    {
      "term": "FLUSHING",
      "count": 42
    },
    {
      "term": "NAUSEA",
      "count": 42
    },
    {
      "term": "COUGH",
      "count": 41
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 41
    },
    {
      "term": "PNEUMONIA",
      "count": 41
    },
    {
      "term": "RENAL INJURY",
      "count": 41
    },
    {
      "term": "DEATH",
      "count": 40
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 40
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 39
    },
    {
      "term": "APNOEA",
      "count": 39
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 39
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 39
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 38
    },
    {
      "term": "PROCEDURAL HYPOTENSION",
      "count": 38
    },
    {
      "term": "AGITATION",
      "count": 37
    },
    {
      "term": "KOUNIS SYNDROME",
      "count": 37
    },
    {
      "term": "SHOCK",
      "count": 37
    },
    {
      "term": "ELECTROCARDIOGRAM ST SEGMENT ELEVATION",
      "count": 36
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 35
    },
    {
      "term": "ARTHROPATHY",
      "count": 35
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 35
    },
    {
      "term": "FINGER DEFORMITY",
      "count": 35
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 35
    },
    {
      "term": "SEPSIS",
      "count": 35
    },
    {
      "term": "MUSCLE RIGIDITY",
      "count": 34
    },
    {
      "term": "MUSCLE TWITCHING",
      "count": 34
    },
    {
      "term": "TENOSYNOVITIS",
      "count": 34
    },
    {
      "term": "UNRESPONSIVE TO STIMULI",
      "count": 34
    },
    {
      "term": "ANHEDONIA",
      "count": 33
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 33
    },
    {
      "term": "VOMITING",
      "count": 33
    },
    {
      "term": "ASTHENIA",
      "count": 32
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 32
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 32
    },
    {
      "term": "AIRWAY PEAK PRESSURE INCREASED",
      "count": 31
    },
    {
      "term": "LARYNGOSPASM",
      "count": 30
    },
    {
      "term": "PREMATURE DELIVERY",
      "count": 30
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 30
    }
  ]
}