{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 1250
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1154
    },
    {
      "term": "HYPOTENSION",
      "count": 1122
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 989
    },
    {
      "term": "CARDIAC ARREST",
      "count": 676
    },
    {
      "term": "DRUG INTERACTION",
      "count": 480
    },
    {
      "term": "TACHYCARDIA",
      "count": 421
    },
    {
      "term": "BRADYCARDIA",
      "count": 414
    },
    {
      "term": "OFF LABEL USE",
      "count": 405
    },
    {
      "term": "BRONCHOSPASM",
      "count": 364
    },
    {
      "term": "RASH",
      "count": 282
    },
    {
      "term": "URTICARIA",
      "count": 279
    },
    {
      "term": "HYPOXIA",
      "count": 261
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 261
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 260
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 234
    },
    {
      "term": "CIRCULATORY COLLAPSE",
      "count": 223
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 205
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 197
    },
    {
      "term": "HYPERTHERMIA MALIGNANT",
      "count": 197
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 188
    },
    {
      "term": "ERYTHEMA",
      "count": 182
    },
    {
      "term": "DYSPNOEA",
      "count": 178
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 167
    },
    {
      "term": "RENAL FAILURE",
      "count": 159
    },
    {
      "term": "NEUROMUSCULAR BLOCK PROLONGED",
      "count": 156
    },
    {
      "term": "HYPERTENSION",
      "count": 146
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 146
    },
    {
      "term": "PREMATURE BABY",
      "count": 146
    },
    {
      "term": "PAIN",
      "count": 145
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 143
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 140
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 138
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 133
    },
    {
      "term": "VENTRICULAR TACHYCARDIA",
      "count": 132
    },
    {
      "term": "ANGIOEDEMA",
      "count": 131
    },
    {
      "term": "RESPIRATORY ARREST",
      "count": 129
    },
    {
      "term": "DELAYED RECOVERY FROM ANAESTHESIA",
      "count": 127
    },
    {
      "term": "STRESS CARDIOMYOPATHY",
      "count": 123
    },
    {
      "term": "VENTRICULAR FIBRILLATION",
      "count": 120
    },
    {
      "term": "OVERDOSE",
      "count": 118
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 116
    },
    {
      "term": "SEPSIS",
      "count": 116
    },
    {
      "term": "HAEMODYNAMIC INSTABILITY",
      "count": 115
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 115
    },
    {
      "term": "PNEUMONIA",
      "count": 115
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 113
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 112
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 112
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 111
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 110
    },
    {
      "term": "PULSELESS ELECTRICAL ACTIVITY",
      "count": 110
    },
    {
      "term": "PYREXIA",
      "count": 109
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 104
    },
    {
      "term": "RECURRENCE OF NEUROMUSCULAR BLOCKADE",
      "count": 104
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 104
    },
    {
      "term": "DEATH",
      "count": 103
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 102
    },
    {
      "term": "NAUSEA",
      "count": 100
    },
    {
      "term": "ANXIETY",
      "count": 99
    },
    {
      "term": "SHOCK",
      "count": 99
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 97
    },
    {
      "term": "VOMITING",
      "count": 95
    },
    {
      "term": "PARALYSIS",
      "count": 94
    },
    {
      "term": "HAEMORRHAGE",
      "count": 91
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 87
    },
    {
      "term": "HYPOVENTILATION",
      "count": 87
    },
    {
      "term": "KOUNIS SYNDROME",
      "count": 87
    },
    {
      "term": "AGITATION",
      "count": 86
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 86
    },
    {
      "term": "APNOEA",
      "count": 83
    },
    {
      "term": "RESPIRATORY ACIDOSIS",
      "count": 83
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 82
    },
    {
      "term": "PREMATURE DELIVERY",
      "count": 82
    },
    {
      "term": "FLUSHING",
      "count": 81
    },
    {
      "term": "PROCEDURAL HYPOTENSION",
      "count": 81
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 77
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 77
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 77
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 76
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 76
    },
    {
      "term": "COUGH",
      "count": 75
    },
    {
      "term": "DYSKINESIA",
      "count": 75
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 75
    },
    {
      "term": "TROPONIN INCREASED",
      "count": 74
    },
    {
      "term": "DRUG EFFECT DECREASED",
      "count": 73
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 73
    },
    {
      "term": "PNEUMOTHORAX",
      "count": 73
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 72
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 72
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 71
    },
    {
      "term": "COMA",
      "count": 71
    },
    {
      "term": "INJURY",
      "count": 71
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 71
    },
    {
      "term": "POST PROCEDURAL COMPLICATION",
      "count": 71
    },
    {
      "term": "TOXIC ENCEPHALOPATHY",
      "count": 71
    },
    {
      "term": "UNRESPONSIVE TO STIMULI",
      "count": 71
    },
    {
      "term": "ANAESTHETIC COMPLICATION",
      "count": 70
    },
    {
      "term": "BLOOD POTASSIUM INCREASED",
      "count": 70
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 69
    }
  ]
}