{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 314
    },
    {
      "term": "DIARRHOEA",
      "count": 270
    },
    {
      "term": "OFF LABEL USE",
      "count": 264
    },
    {
      "term": "HEPATIC ENCEPHALOPATHY",
      "count": 245
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 184
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 174
    },
    {
      "term": "NAUSEA",
      "count": 171
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 163
    },
    {
      "term": "ANAEMIA",
      "count": 160
    },
    {
      "term": "PNEUMONIA",
      "count": 149
    },
    {
      "term": "VOMITING",
      "count": 146
    },
    {
      "term": "DYSPNOEA",
      "count": 130
    },
    {
      "term": "DRUG INTERACTION",
      "count": 128
    },
    {
      "term": "FATIGUE",
      "count": 126
    },
    {
      "term": "ASCITES",
      "count": 125
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 119
    },
    {
      "term": "HEADACHE",
      "count": 119
    },
    {
      "term": "DEATH",
      "count": 114
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 107
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 105
    },
    {
      "term": "DIZZINESS",
      "count": 103
    },
    {
      "term": "ASTHENIA",
      "count": 102
    },
    {
      "term": "PYREXIA",
      "count": 100
    },
    {
      "term": "RENAL FAILURE",
      "count": 93
    },
    {
      "term": "HEPATIC CIRRHOSIS",
      "count": 91
    },
    {
      "term": "SEPSIS",
      "count": 77
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 77
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 76
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 76
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 74
    },
    {
      "term": "CROHN^S DISEASE",
      "count": 74
    },
    {
      "term": "PAIN",
      "count": 74
    },
    {
      "term": "FALL",
      "count": 73
    },
    {
      "term": "HYPOTENSION",
      "count": 73
    },
    {
      "term": "DEHYDRATION",
      "count": 71
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 70
    },
    {
      "term": "MENTAL STATUS CHANGES",
      "count": 69
    },
    {
      "term": "CONSTIPATION",
      "count": 68
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 67
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 67
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 65
    },
    {
      "term": "AMMONIA INCREASED",
      "count": 64
    },
    {
      "term": "ARTHRALGIA",
      "count": 63
    },
    {
      "term": "DECREASED APPETITE",
      "count": 60
    },
    {
      "term": "MALAISE",
      "count": 59
    },
    {
      "term": "NEUTROPENIA",
      "count": 59
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 58
    },
    {
      "term": "FREQUENT BOWEL MOVEMENTS",
      "count": 57
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 57
    },
    {
      "term": "PRURITUS",
      "count": 57
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 57
    },
    {
      "term": "COUGH",
      "count": 56
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 55
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 53
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 53
    },
    {
      "term": "RECTAL HAEMORRHAGE",
      "count": 53
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 52
    },
    {
      "term": "PANCREATITIS",
      "count": 51
    },
    {
      "term": "SMALL INTESTINAL OBSTRUCTION",
      "count": 51
    },
    {
      "term": "SOMNOLENCE",
      "count": 51
    },
    {
      "term": "BACK PAIN",
      "count": 50
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 50
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 50
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 49
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 49
    },
    {
      "term": "RASH",
      "count": 49
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 49
    },
    {
      "term": "LIVER DISORDER",
      "count": 48
    },
    {
      "term": "QUALITY OF LIFE DECREASED",
      "count": 48
    },
    {
      "term": "HAEMATOCHEZIA",
      "count": 45
    },
    {
      "term": "HYPOGLYCAEMIA",
      "count": 45
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 43
    },
    {
      "term": "INCONTINENCE",
      "count": 42
    },
    {
      "term": "LEUKOPENIA",
      "count": 41
    },
    {
      "term": "LACTIC ACIDOSIS",
      "count": 40
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 39
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE INFECTION",
      "count": 39
    },
    {
      "term": "CARDIAC ARREST",
      "count": 38
    },
    {
      "term": "COVID-19",
      "count": 38
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 38
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 38
    },
    {
      "term": "NERVE INJURY",
      "count": 38
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 38
    },
    {
      "term": "HOSPITALISATION",
      "count": 37
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 37
    },
    {
      "term": "DEPRESSION",
      "count": 36
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 36
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 36
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 36
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 36
    },
    {
      "term": "CHEST PAIN",
      "count": 35
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 35
    },
    {
      "term": "JAUNDICE",
      "count": 34
    },
    {
      "term": "PANCYTOPENIA",
      "count": 34
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 33
    },
    {
      "term": "DISSEMINATED INTRAVASCULAR COAGULATION",
      "count": 33
    },
    {
      "term": "EPISTAXIS",
      "count": 33
    },
    {
      "term": "HYPERAMMONAEMIA",
      "count": 33
    },
    {
      "term": "HYPERAMMONAEMIC ENCEPHALOPATHY",
      "count": 33
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 33
    }
  ]
}